Oral anticoagulants for left atrial thrombus resolution in nonvalvular atrial fibrillation or flutter: Building the pyramid of evidence for off-label drug use. 2019

Aliza Hussain, and William E Katz, and Michael V Genuardi, and Aditya Bhonsale, and Sandeep K Jain, and Krishna Kancharla, and Samir Saba, and Alaa A Shalaby, and Andrew H Voigt, and Norman C Wang
Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, Texas.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000925 Anticoagulants Agents that prevent BLOOD CLOTTING. Anticoagulant Agent,Anticoagulant Drug,Anticoagulant,Anticoagulant Agents,Anticoagulant Drugs,Anticoagulation Agents,Indirect Thrombin Inhibitors,Agent, Anticoagulant,Agents, Anticoagulant,Agents, Anticoagulation,Drug, Anticoagulant,Drugs, Anticoagulant,Inhibitors, Indirect Thrombin,Thrombin Inhibitors, Indirect
D001281 Atrial Fibrillation Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation. Auricular Fibrillation,Familial Atrial Fibrillation,Paroxysmal Atrial Fibrillation,Persistent Atrial Fibrillation,Atrial Fibrillation, Familial,Atrial Fibrillation, Paroxysmal,Atrial Fibrillation, Persistent,Atrial Fibrillations,Atrial Fibrillations, Familial,Atrial Fibrillations, Paroxysmal,Atrial Fibrillations, Persistent,Auricular Fibrillations,Familial Atrial Fibrillations,Fibrillation, Atrial,Fibrillation, Auricular,Fibrillation, Familial Atrial,Fibrillation, Paroxysmal Atrial,Fibrillation, Persistent Atrial,Fibrillations, Atrial,Fibrillations, Auricular,Fibrillations, Familial Atrial,Fibrillations, Paroxysmal Atrial,Fibrillations, Persistent Atrial,Paroxysmal Atrial Fibrillations,Persistent Atrial Fibrillations
D013927 Thrombosis Formation and development of a thrombus or blood clot in BLOOD VESSELS. Atherothrombosis,Thrombus,Blood Clot,Blood Clots,Thromboses
D014859 Warfarin An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide. 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one,Aldocumar,Apo-Warfarin,Coumadin,Coumadine,Gen-Warfarin,Marevan,Tedicumar,Warfant,Warfarin Potassium,Warfarin Sodium,Potassium, Warfarin,Sodium, Warfarin
D056687 Off-Label Use The practice of prescribing or using a drug or a vaccine outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition. Dose-Sparing Drug Use,Fractional Dose Drug Use,Off-Label Prescribing,Reduced-Dose Drug Use,Unlabeled Indication,Dose Sparing Drug Use,Dose-Sparing Drug Uses,Indication, Unlabeled,Off Label Prescribing,Off Label Use,Off-Label Prescribings,Off-Label Uses,Prescribing, Off-Label,Reduced Dose Drug Use,Reduced-Dose Drug Uses,Unlabeled Indications
D020517 Atrial Appendage Ear-shaped appendage of either atrium of the heart. (Dorland, 28th ed) Auricular Appendage,Heart Atrium Appendage,Atrium Appendage,Appendage, Atrial,Appendage, Atrium,Appendage, Auricular,Appendage, Heart Atrium,Appendages, Atrial,Appendages, Atrium,Appendages, Auricular,Appendages, Heart Atrium,Atrial Appendages,Atrium Appendage, Heart,Atrium Appendages,Auricular Appendages,Heart Atrium Appendages

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