BIOMAT Database Logo BIOMAT Database Logo

Gene frequencies and genetic linkage disequilibrium for the HLA-linked genes Bf, C2, C4S, C4F, 21-hydroxylase deficiency, and glyoxalase I. 1979

G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont

UI MeSH Term Description Entries
D007791 Lactoylglutathione Lyase An enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. EC 4.4.1.5. Glyoxalase I,Lactoyl Glutathione Lyase,Methylglyoxalase,Glutathione Lyase, Lactoyl,Lyase, Lactoyl Glutathione,Lyase, Lactoylglutathione
D008040 Genetic Linkage The co-inheritance of two or more non-allelic GENES due to their being located more or less closely on the same CHROMOSOME. Genetic Linkage Analysis,Linkage, Genetic,Analyses, Genetic Linkage,Analysis, Genetic Linkage,Genetic Linkage Analyses,Linkage Analyses, Genetic,Linkage Analysis, Genetic
D008190 Lyases A class of enzymes that catalyze the cleavage of C-C, C-O, and C-N, and other bonds by other means than by hydrolysis or oxidation. (Enzyme Nomenclature, 1992) EC 4. Desmolase,Desmolases,Lyase
D011110 Polymorphism, Genetic The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level. Gene Polymorphism,Genetic Polymorphism,Polymorphism (Genetics),Genetic Polymorphisms,Gene Polymorphisms,Polymorphism, Gene,Polymorphisms (Genetics),Polymorphisms, Gene,Polymorphisms, Genetic
D001789 Blood Group Antigens Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties. Blood Group,Blood Group Antigen,Blood Groups,Antigen, Blood Group,Antigens, Blood Group,Group Antigen, Blood,Group, Blood,Groups, Blood
D002874 Chromosome Mapping Any method used for determining the location of and relative distances between genes on a chromosome. Gene Mapping,Linkage Mapping,Genome Mapping,Chromosome Mappings,Gene Mappings,Genome Mappings,Linkage Mappings,Mapping, Chromosome,Mapping, Gene,Mapping, Genome,Mapping, Linkage,Mappings, Chromosome,Mappings, Gene,Mappings, Genome,Mappings, Linkage
D005787 Gene Frequency The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION. Allele Frequency,Genetic Equilibrium,Equilibrium, Genetic,Allele Frequencies,Frequencies, Allele,Frequencies, Gene,Frequency, Allele,Frequency, Gene,Gene Frequencies
D006680 HLA Antigens Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases. Human Leukocyte Antigen,Human Leukocyte Antigens,Leukocyte Antigens,HL-A Antigens,Antigen, Human Leukocyte,Antigens, HL-A,Antigens, HLA,Antigens, Human Leukocyte,Antigens, Leukocyte,HL A Antigens,Leukocyte Antigen, Human,Leukocyte Antigens, Human
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000312 Adrenal Hyperplasia, Congenital A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders. Congenital Adrenal Hyperplasia,Hyperplasia, Congenital Adrenal,Adrenal Hyperplasias, Congenital,Congenital Adrenal Hyperplasias,Hyperplasias, Congenital Adrenal

Related Publications

G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Possible genetic linkage disequilibrium between HLA and the 21-hydroxylase deficiency gene (congenital adrenal hyperplasia).
June 1979, Transplantation proceedings,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Linkage relationship of C2 deficiency, HLA and glyoxalase I loci.
January 1979, Vox sanguinis,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Genetic linkage of a locus for erythrocyte glyoxalase (GLO) with HLA and Bf.
January 1976, Cytogenetics and cell genetics,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Genetic linkage of a locus for erythrocyte glyoxalase (GLO) with HLA and Bf.
January 1976, Birth defects original article series,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Close genetic linkage between HLA and congenital adrenal hyperplasia (21-hydroxylase deficiency).
January 1977, Lancet (London, England),
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Linkage and association between HLA and 21-hydroxylase deficiency.
October 1980, Journal of medical genetics,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
HLA class I-, complement C4- and 21-hydroxylase probes in the genetic analysis of 21-hydroxylase deficiency.
June 1990, Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Genetic linkage and HLA association in congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
May 1983, Human immunology,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
Population genetic studies of HLA-G: allele frequencies and linkage disequilibrium with HLA-A1.
December 1996, Journal of reproductive immunology,
G J O'Neill, and M S Pollack, and S Y Yang, and L S Levine, and M I New, and B Dupont
HLA-linked complement polymorphisms (C2, BF) in psoriasis.
January 1983, Archives of dermatological research,
Copied contents to your clipboard!