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1. The bile salts of three frog species of the genus Ptychadena and of Rana catesbeiana have been compared with those of their tadpoles. For R. catesbeiana comparison was made of the bile salts in at least ten of the recognized stages of tadpole metamorphosis. 2. In all cases, adult bile salts were more complex than those of the tadpoles. 3. In R. catesbeiana after stage 18, 26-deoxy-5 alpha-ranol was hydroxylated to form 5 alpha-ranol (27-nor-5 alpha-cholestane-3 alpha, 7 alpha, 12 alpha, 24 xi, 26-pentol) and at least two other bile alcohols appeared in solvolysed bile salts. 4. Tadpole bile salts were not found to be biochemically more primitive than those of fully metamorphosed frogs; in some, but not all, cases tadpole bile alcohols could be regarded as biochemical precursors of those in the adult frogs. 5. Detailed evidence for the structure of the bile salts from mass-spectral fragmentation patterns has been deposited as Supplementary Publication SUP 50097 (2 pages) at the British Library Lending Division, Boston Spa, Wetherby, West Yorkshire LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1978) 169, 5.
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
January 1983,
Comparative biochemistry and physiology. B, Comparative biochemistry,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
February 1977,
General and comparative endocrinology,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
April 1994,
General and comparative endocrinology,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
October 1979,
Endocrinologia japonica,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
February 1973,
Developmental biology,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
January 1966,
Nihon Ika Daigaku zasshi,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
April 1973,
Respiration physiology,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
October 1975,
Developmental biology,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
January 2022,
Frontiers in endocrinology,
I G Anderson, and
T Briggs, and
G A Haslewood, and
R S Oldham, and
H Schären, and
L Tökés
August 1968,
The Biological bulletin,
