Biomaterial Database

Hypotension: an unusual presentation of vitamin B12 deficiency, with complete recovery following cyanocobalamin therapy. 2019

Zohaib Yousaf, and Almurtada Razok, and Abdel-Naser Elzouki, and Taher Sabobeh

Internal Medicine, Hamad Medical Corporation Department of Medical Education, Doha, Qatar zohaib.yousaf@gmail.com.

Vitamin B12 deficiency and its sequelae are well described and reported, especially in vegetarians. However, its association with haemodynamic instability is not well identified. We report a case of a young man, previously healthy, presenting with fever, hypotension requiring vasopressors and pancytopenia. Extensive workup was unrevealing for possible infective, inflammatory or endocrine causes except for vitamin B12 deficiency. Fever and haematological parameters stabilised after adequate supplementation of cyanocobalamin (vitamin B12).

UI	MeSH Term	Description	Entries
D007022	Hypotension	Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.	Blood Pressure, Low,Hypotension, Vascular,Low Blood Pressure,Vascular Hypotension
D008297	Male		Males
D010198	Pancytopenia	Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.	Pancytopenias
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005334	Fever	An abnormal elevation of body temperature, usually as a result of a pathologic process.	Pyrexia,Fevers,Pyrexias
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014676	Diet, Vegetarian	The dietary practice of completely avoiding meat or fish products in the DIET, consuming VEGETABLES, CEREALS, and NUTS. Some vegetarian diets called lacto-ovo also include milk and egg products.	Lacto-Ovo Vegetarian Diet,Lacto-Vegetarian Diet,Vegetarian Diet,Vegetarianism,Diet, Lacto-Ovo Vegetarian,Diet, Lacto-Vegetarian,Diets, Lacto-Ovo Vegetarian,Diets, Lacto-Vegetarian,Diets, Vegetarian,Lacto Ovo Vegetarian Diet,Lacto Vegetarian Diet,Lacto-Ovo Vegetarian Diets,Lacto-Vegetarian Diets,Vegetarian Diet, Lacto-Ovo,Vegetarian Diets,Vegetarian Diets, Lacto-Ovo
D014803	Vitamin B Complex	A group of water-soluble vitamins, some of which are COENZYMES.	B Vitamin,B Vitamins,Neurobion,Vitamin, B
D014805	Vitamin B 12	A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.	Cobalamin,Cyanocobalamin,Cobalamins,Eritron,Vitamin B12,B 12, Vitamin,B12, Vitamin