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1. Superoxide dismutase (superoxide: superoxide oxido-reductase, E.C. 1.15.1.1) in different species was determined quantitatively and qualitatively. Although quantitative differences were minor, there were significant differences in the isoenzyme patterns among the species. 2. No quantitative differences were found in superoxide dismutase (SOD) activities in the brains of mice between 1 and 23 days of age. The mitochondrial isoenzyme increased with age, attaining maximal levels between 9 and 12 days. In the six, regions of adult rat brain studied, highest values of SOD were found in the hypothalamus and lowest in the cortex. 3. SOD levels generally were lower in several transplantable mouse and rat tumors than in normal tissues of these species. Mn-SOD was not detected in the tumors studied by the methods employed.
J N Van Balgooy, and
E Roberts
September 1984,
The Biochemical journal,
J N Van Balgooy, and
E Roberts
March 1992,
Cancer genetics and cytogenetics,
J N Van Balgooy, and
E Roberts
July 1981,
Cancer research,
J N Van Balgooy, and
E Roberts
January 1982,
Vestnik Akademii meditsinskikh nauk SSSR,
J N Van Balgooy, and
E Roberts
May 1982,
Cancer research,
J N Van Balgooy, and
E Roberts
January 1976,
Doklady Akademii nauk SSSR,
J N Van Balgooy, and
E Roberts
June 1983,
Biochemical and biophysical research communications,
J N Van Balgooy, and
E Roberts
January 1980,
Acta physiologica Scandinavica. Supplementum,
J N Van Balgooy, and
E Roberts
April 1973,
Human heredity,
J N Van Balgooy, and
E Roberts
May 1994,
Laboratory investigation; a journal of technical methods and pathology,
