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To investigate the relationship between the plasma somatomedin-C level and diabetic retinopathy, especially in different stages of the disease, plasma somatomedin-C levels were measured in 72 patients with noninsulin-dependent diabetes mellitus accompanied by or without retinopathy and in 37 normal control subjects. The stage of retinopathy was assessed by ophthalmoscopy and fluorescein angiography. Plasma somatomedin-C levels were significantly greater in the diabetic patients with retinopathy than in the age-matched normal controls (P less than 0.01). Plasma somatomedin-C level in the patients with proliferative retinopathy was 0.60 +/- 0.30 (mean +/- SD) IU/ml (n = 24), which was significantly greater than that in the normal controls (0.41 +/- 0.18 IU/ml) (P less than 0.01). However, the patients in different stages of diabetic retinopathy did not differ significantly from each other in their plasma somatomedin-C levels.
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
January 1989,
Acta diabetologica latina,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
July 1983,
Clinical endocrinology,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
October 1987,
Diabetes,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
February 1986,
Nihon Sanka Fujinka Gakkai zasshi,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
June 1989,
Metabolism: clinical and experimental,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
September 1984,
Diabetes research (Edinburgh, Scotland),
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
December 1988,
Biochemical medicine and metabolic biology,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
November 1990,
Diabetes,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
September 1977,
Diabetes,
K Sato, and
T Ikeda, and
T Miki, and
Y Nishizawa, and
H Morii
June 1984,
Diabetes,
