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Monte Carlo evaluation of specific dose constants in water for 125I seeds. 1988

J F Williamson
Department of Radiation Oncology, University of Arizona, Tucson 85724.

To clinically utilize relative three-dimensional dose distribution data for 125I seeds in water, the specific dose constant must be known. This constant is the ratio of absolute dose rate in medium, 1 cm from the source on its transverse bisector, to source strength. We have used the Monte Carlo method to calculate specific dose constants in water for three types of 125I seeds (models 6711, 6701, and 6702). Our photon transport code realistically models the complex internal structure of these interstitial sources as well as the exposure standardization experiments conducted at the National Bureau of Standards which form the basis of 125I source strength specification. In addition, relative attenuation factors for the three seed types are presented. Our results indicate that published data overestimate the specific dose constant by 10% to 14%.

UI MeSH Term Description Entries
D007457 Iodine Radioisotopes Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes. Radioisotopes, Iodine
D008962 Models, Theoretical Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment. Experimental Model,Experimental Models,Mathematical Model,Model, Experimental,Models (Theoretical),Models, Experimental,Models, Theoretic,Theoretical Study,Mathematical Models,Model (Theoretical),Model, Mathematical,Model, Theoretical,Models, Mathematical,Studies, Theoretical,Study, Theoretical,Theoretical Model,Theoretical Models,Theoretical Studies
D009010 Monte Carlo Method In statistics, a technique for numerically approximating the solution of a mathematical problem by studying the distribution of some random variable, often generated by a computer. The name alludes to the randomness characteristic of the games of chance played at the gambling casinos in Monte Carlo. (From Random House Unabridged Dictionary, 2d ed, 1993) Method, Monte Carlo
D009874 Operations Research A group of techniques developed to apply scientific methods and tools to solve the problems of DECISION MAKING in complex organizations and systems. Operations research searches for optimal solutions in situations of conflicting GOALS and makes use of mathematical models from which solutions for actual problems may be derived. (From Psychiatric Dictionary, 6th ed) Operational Research,Research, Operational,Research, Operations
D011879 Radiotherapy Dosage The total amount of radiation absorbed by tissues as a result of radiotherapy. Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D001918 Brachytherapy A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues. Curietherapy,Implant Radiotherapy,Plaque Therapy, Radioisotope,Radioisotope Brachytherapy,Radiotherapy, Interstitial,Radiotherapy, Intracavity,Radiotherapy, Surface,Brachytherapy, Radioisotope,Interstitial Radiotherapy,Intracavity Radiotherapy,Radioisotope Plaque Therapy,Radiotherapy, Implant,Surface Radiotherapy,Therapy, Radioisotope Plaque
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000388 Air The mixture of gases present in the earth's atmosphere consisting of oxygen, nitrogen, carbon dioxide, and small amounts of other gases.
D001703 Biophysics The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things. Mechanobiology
D055592 Biophysical Phenomena The physical characteristics and processes of biological systems. Biophysical Concepts,Biophysical Processes,Biophysical Phenomenon,Biophysical Process,Biophysical Concept,Concept, Biophysical,Concepts, Biophysical,Phenomena, Biophysical,Phenomenon, Biophysical,Process, Biophysical,Processes, Biophysical

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