Among the most important complaints of people exposed to noise are the feelings of resentment and annoyance, and the changes in mental conditions, which are among the main psychological consequences affecting the concentration and accuracy of workers. This study was designed to investigate the relationship between annoyance and cognitive performance of workers exposed to chronic noise. This is a descriptive-analytical study conducted on workers in an automotive company. Three hundred workers exposed to noise were entered into the study in two groups: administrative (150 people) and industrial (150 people). The Tower of London and the Stroop computerized psychological tests were used to determine the cognitive status of the workers, and a questionnaire with numbered questions (numbered 1 to 11) was used in order to determine their level of annoyance. There was a significant correlation between the workers' cognitive performance and annoyance levels (P value <0.001). Linear regression results showed that cognitive performance had a significant relationship with the received sound intensity, while the workers' annoyance had a significant relationship with cognitive performance only in the number of wrong answers, the number of unanswered questions, and the number of correct answers in the Stroop test (P value <0.001). The researchers concluded that exposure to chronic noise in work environments could bring about occupational annoyance, and consequently, cognitive disorders, which could increase the risk of errors. More studies are needed to further explore this relationship.