Tobacco-specific N-nitrosamines in the saliva of habitual male snuff dippers. 1988

B G Osterdahl, and S Slorach
Swedish National Food Administration, Uppsala.

Saliva was collected every ten minutes from habitual male snuff dippers and analysed for tobacco-specific N-nitrosamines (TSNA). Detectable levels of at least two TSNA were found in all samples collected between 10 and 30 minutes after the snuff had been placed in the mouth. Total concentrations of TSNA up to 241 ng/g were found in the saliva. Trace levels of TSNA were still found in the saliva 20 minutes after the snuff had been removed.

UI MeSH Term Description Entries
D008297 Male Males
D009602 Nitrosamines A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties. Nitrosamine
D010947 Plants, Toxic Plants or plant parts which are harmful to man or other animals. Plants, Poisonous,Plant, Poisonous,Plant, Toxic,Poisonous Plant,Poisonous Plants,Toxic Plant,Toxic Plants
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012463 Saliva The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin. Salivas
D014026 Nicotiana A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; the dried leaves of Nicotiana tabacum are used for SMOKING. Tobacco Plant,Nicotiana tabacum,Plant, Tobacco,Plants, Tobacco,Tobacco Plants
D014030 Tobacco, Smokeless Any product of NICOTIANA TABACUM that is not smoked but is either inhaled through the nose, chewed, or stored in cheek pouches. Chewing Tobacco,Oral Tobacco,Smokeless Tobacco,Snuff,Dipping Tobacco,Gutka,Gutka Tobacco,Mint Snuff,Snus,Chewing Tobaccos,Dipping Tobaccos,Gutka Tobaccos,Gutkas,Snuff, Mint,Tobacco, Chewing,Tobacco, Dipping,Tobacco, Gutka,Tobacco, Oral,Tobaccos, Chewing,Tobaccos, Dipping,Tobaccos, Gutka,Tobaccos, Smokeless

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