Biomaterial Database

Fuchs' heterochromic iridocyclitis in blacks. 1988

B R Tabbut, and H H Tessler, and D Williams

Department of Ophthalmology, Eye and Ear Infirmary, University of Illinois College of Medicine, Chicago 60612.

Fuchs' heterochromic iridocyclitis (FHI) is a frequently overlooked cause of anterior uveitis. Improper diagnosis may lead to unnecessary therapy. Dark brown irides may demonstrate heterochromia poorly. We believe that FHI may be overlooked in blacks because of a frequent lack of obvious heterochromia and the frequent presence of iris nodules. Heterochromia is not necessary for the diagnosis of FHI if other clinical features of the syndrome are present. In our series of 54 whites and 13 blacks with FHI, heterochromia occurred in 50 (92%) whites and ten (76%) blacks (nonsignificant difference). Iris nodules occurred in 11 (20%) whites and four (30%) blacks (not significant). Statistically significant differences occurred with cataract/aphakia in 41 (75%) whites and three (23%) blacks and with glaucoma in six (11%) whites and five (38%) blacks.

UI	MeSH Term	Description	Entries
D007499	Iris Diseases	Diseases, dysfunctions, or disorders of or located in the iris.	Disease, Iris,Diseases, Iris,Iris Disease
D002386	Cataract	Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)	Cataract, Membranous,Lens Opacities,Pseudoaphakia,Cataracts,Cataracts, Membranous,Lens Opacity,Membranous Cataract,Membranous Cataracts,Opacities, Lens,Opacity, Lens,Pseudoaphakias
D005127	Eye Color	Color of the iris.	Color, Eye,Colors, Eye,Eye Colors
D005901	Glaucoma	An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)	Glaucomas
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000367	Age Factors	Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.	Age Reporting,Age Factor,Factor, Age,Factors, Age
D001036	Aphakia, Postcataract	Absence of the crystalline lens resulting from cataract extraction.	Aphakic Eye, Postcataract,Aphakias, Postcataract,Postcataract Aphakia,Postcataract Aphakias,Postcataract Aphakic Eye,Postcataract Aphakic Eyes
D014606	Uveitis, Anterior	Inflammation of the anterior uvea comprising the iris, angle structures, and the ciliary body. Manifestations of this disorder include ciliary injection, exudation into the anterior chamber, iris changes, and adhesions between the iris and lens (posterior synechiae). Intraocular pressure may be increased or reduced.	Anterior Uveitides,Anterior Uveitis,Uveitides, Anterior
D014792	Visual Acuity	Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.	Acuities, Visual,Acuity, Visual,Visual Acuities
D044383	Black People	Persons having origins in any of the black racial groups of AFRICA. Note that OMB category BLACK OR AFRICAN AMERICAN is available for the United States population groups. Race and ethnicity terms, as used in the federal government, are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies.	African Continental Ancestry Group,Black Person,Negroid Race,Black Peoples,Black Persons,Negroid Races,People, Black,Person, Black,Persons, Black,Race, Negroid