Cystic fibrosis is a genetically determined disease. It is currently detected right after birth thanks to a screening program. This early detection allows for quick treatment inclusion. Cystic fibrosis therapy has a comprehensive character. The way of nutrition is also very important. The aim of this study was to evaluate the benefits and risks of enteral nutrition in patients with cystic fibrosis. 53 people with cystic fibrosis participated in the study (15 men, 38 women). Qualification for the study required the fulfillment of three conditions: enteral nutrition used for at least one month, no increase in body weight when using a high energy diet, underweight. The research was carried with use of self-constructed questionnaire. The mean age of the respondents was 19.9 ± 4 years. The median weight gain after enteral nutrition was 7 kg. Most (n = 42, 79.2%) did not report any side effects. Few reported local infections (n = 9; 17%) or prolapse of the balloon (n = 2, 3.8%). On the other hand, everyone reported benefits - it was mainly weight gain and improved quality of life. In some cases (n = 22, 41.5%) with the use of enteral nutrition, a decrease in the frequency of respiratory infections was observed. Enteral nutrition is a beneficial method in those patients with cystic fibrosis, in whom high-energy oral nutrition is inefficient.