BIOMAT Database Logo BIOMAT Database Logo

Novel antifungal antibiotics octacosamicins A and B. I. Taxonomy, fermentation and isolation, physico-chemical properties and biological activities. 1988

K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Institute of Microbial Chemistry, Tokyo, Japan.

Two antifungal antibiotics octacosamicins A and B were isolated from the culture broth of a strain of actinomycetes, which was identified as a strain of Amycolatopsis. These antibiotics were isolated by resin adsorption and purified by column chromatography and preparative HPLC. Both antibiotics were found to be new substances from their physico-chemical properties. They showed broad antifungal spectra.

UI MeSH Term Description Entries
D002621 Chemistry A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.
D005285 Fermentation Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID. Fermentations
D006146 Guanidines A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
D000192 Actinomycetales An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments. Corynebacteriaceae,Coryneform Group
D000935 Antifungal Agents Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics
D055598 Chemical Phenomena The composition, structure, conformation, and properties of atoms and molecules, and their reaction and interaction processes. Chemical Concepts,Chemical Processes,Physical Chemistry Concepts,Physical Chemistry Processes,Physicochemical Concepts,Physicochemical Phenomena,Physicochemical Processes,Chemical Phenomenon,Chemical Process,Physical Chemistry Phenomena,Physical Chemistry Process,Physicochemical Phenomenon,Physicochemical Process,Chemical Concept,Chemistry Process, Physical,Chemistry Processes, Physical,Concept, Chemical,Concept, Physical Chemistry,Concept, Physicochemical,Concepts, Chemical,Concepts, Physical Chemistry,Concepts, Physicochemical,Phenomena, Chemical,Phenomena, Physical Chemistry,Phenomena, Physicochemical,Phenomenon, Chemical,Phenomenon, Physicochemical,Physical Chemistry Concept,Physicochemical Concept,Process, Chemical,Process, Physical Chemistry,Process, Physicochemical,Processes, Chemical,Processes, Physical Chemistry,Processes, Physicochemical

Related Publications

K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Novel antifungal antibiotics maniwamycins A and B. I. Taxonomy of the producing organism, fermentation, isolation, physico-chemical properties and biological properties.
November 1989, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Kigamicins, novel antitumor antibiotics. I. Taxonomy, isolation, physico-chemical properties and biological activities.
December 2003, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Studies on new antibiotics SF2415. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
June 1987, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Helvecardins A and B, novel glycopeptide antibiotics. I. Taxonomy, fermentation, isolation and physico-chemical properties.
March 1991, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Karnamicin, a complex of new antifungal antibiotics. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties.
June 1989, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties.
October 1994, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Novel antibiotics, amythiamicins. I. Taxonomy, fermentation, isolation, physico-chemical properties, and antimicrobial activity.
June 1994, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
Novel antibiotics, furaquinocins A and B. Taxonomy, fermentation, isolation and physico-chemical and biological characteristics.
March 1990, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
New antiviral antibiotics, kistamicins A and B. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
December 1993, The Journal of antibiotics,
K Dobashi, and N Matsuda, and M Hamada, and H Naganawa, and T Takita, and T Takeuchi
A new antimitotic substance, FR182877. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
February 2000, The Journal of antibiotics,
Copied contents to your clipboard!