BIOMAT Database Logo BIOMAT Database Logo

Associations of gut microbiota, dietary intake, and serum short-chain fatty acids with fecal short-chain fatty acids. 2020

Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Graduate School of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo 060-8638, Japan.

In recent years, short-chain fatty acids (SCFAs) have been reported to play an important role in maintaining human health. Fecal SCFA concentrations correlate well with colonic SCFA status and gut microbiota composition. However, the associations with the gut microbiota functional pathway, dietary intake, blood SCFAs, and fecal SCFAs remain uncertain. To clarify these relationships, we collected fecal samples, blood samples, and dietary habit data from 12 healthy adults aged 22-51 years. The relative abundance of several SCFA-producing bacteria, gut microbiota diversity, and functional pathways related to SCFA biosynthesis were positively associated with fecal SCFAs even after adjusting for age and sex. Furthermore, fecal acetate was likely to be positively associated with serum acetate. By contrast, dietary intake was not associated with fecal SCFAs. Overall, the present study highlights the potential usefulness of fecal SCFAs as an indicator of the gut microbiota ecosystem and dynamics of SCFAs in the human body.

UI MeSH Term Description Entries

Related Publications

Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Associations of Habitual Dietary Intake With Fecal Short-Chain Fatty Acids and Bowel Functions in Irritable Bowel Syndrome.
March 2022, Journal of clinical gastroenterology,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Associations of Plastic Bottle Exposure with Infant Fecal Microbiota, Short-Chain Fatty Acids, and Growth.
January 2023, Research square,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Associations of Plastic Bottle Exposure with Infant Growth, Fecal Microbiota, and Short-Chain Fatty Acids.
December 2023, Microorganisms,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior.
October 2021, Translational psychiatry,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Reduced fecal short-chain fatty acids levels and the relationship with gut microbiota in IgA nephropathy.
June 2021, BMC nephrology,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Gut Microbiota, Short-Chain Fatty Acids, and Herbal Medicines.
January 2018, Frontiers in pharmacology,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Chronic Psychosocial Stress and Gut Health in Children: Associations With Calprotectin and Fecal Short-Chain Fatty Acids.
October 2017, Psychosomatic medicine,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Alterations of the gut microbiota and fecal short-chain fatty acids in women undergoing assisted reproduction.
January 2024, Reproduction, fertility, and development,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Fecal microbiota transplantation and short-chain fatty acids reduce sepsis mortality by remodeling antibiotic-induced gut microbiota disturbances.
January 2022, Frontiers in immunology,
Ryodai Yamamura, and Koshi Nakamura, and Naoya Kitada, and Tomoyasu Aizawa, and Yu Shimizu, and Kiminori Nakamura, and Tokiyoshi Ayabe, and Takashi Kimura, and Akiko Tamakoshi
Associations of Fecal Short Chain Fatty Acids With Colonic Transit, Fecal Bile Acid, and Food Intake in Irritable Bowel Syndrome.
January 2023, Clinical and translational gastroenterology,
Copied contents to your clipboard!