Spatial transmission risk during the 2007-2010 Q fever epidemic in The Netherlands: Analysis of the farm-to-farm and farm-to-resident transmission. 2020

Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
Department of Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.

Between 2007 and 2010 a Q fever epidemic in Dutch dairy goat farms caused a large Q fever outbreak in human residents in the southern part of the Netherlands. Here we characterize the transmission of Coxiella burnetii, the aetiological agent of Q fever, between infected and susceptible dairy goat farms by estimating a spatial transmission kernel. In addition, we characterize the zoonotic transmission of C. burnetii by estimating the spatial kernel for transmission from infected farms to neighbouring residents. Whereas the range of between-farm transmission is comparable to the scale of the Netherlands, likely due to long-range between-farm contacts such as animal transport, the transmission risk from farms to humans is more localized, although still extending to 10 km and beyond. Within a range of about 10 km, the transmission risk from an infected goat farm to a single resident is of the same order of magnitude as the farm-to-farm transmission risk per animal in a receiving farm. We illustrate how, based on the estimated kernels, spatial patterns of transmission risks between farms and from farms to residents can be calculated and visualized by means of risk maps, offering further insight relevant to policy making in a one-health context.

UI MeSH Term Description Entries
D009426 Netherlands Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, and Sint Maarten, formerly included in the NETHERLANDS ANTILLES. Holland,Kingdom of the Netherlands
D011156 Population Density Number of individuals in a population relative to space. Overpopulation,Population Size,Underpopulation,Densities, Population,Density, Population,Population Densities,Population Sizes
D011778 Q Fever An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC). Coxiella burnetii Fever,Query Fever,Acute Q Fever,Chronic Q Fever,Coxiella burnetii Infection,Coxiella burnetii Vector-Borne Disease,Acute Q Fevers,Chronic Q Fevers,Coxiella burnetii Fevers,Coxiella burnetii Infections,Coxiella burnetii Vector Borne Disease,Fever, Acute Q,Fever, Chronic Q,Fever, Coxiella burnetii,Fever, Q,Fever, Query,Fevers, Acute Q,Fevers, Chronic Q,Fevers, Coxiella burnetii,Fevers, Q,Fevers, Query,Infection, Coxiella burnetii,Infections, Coxiella burnetii,Q Fever, Acute,Q Fever, Chronic,Q Fevers,Q Fevers, Acute,Q Fevers, Chronic,Query Fevers
D005843 Geography The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (From Webster, 3d ed) Factor, Geographic,Factors, Geographic,Geographic Factor,Geographic Factors,Geography, Human,Human Geography
D006041 Goats Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP. Capra,Capras,Goat
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072480 Farms Areas of land set aside to grow crops or raise LIVESTOCK. Farmland,Vineyards,Farm,Farmlands,Vineyard
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D015511 Goat Diseases Diseases of the domestic or wild goat of the genus Capra. Caprine Diseases,Caprine Disease,Disease, Caprine,Disease, Goat,Diseases, Caprine,Diseases, Goat,Goat Disease

Related Publications

Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
April 2014, International journal of environmental health research,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
December 2010, The Netherlands journal of medicine,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
February 2012, FEMS immunology and medical microbiology,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
August 2014, Medecine et maladies infectieuses,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
March 2012, Journal of clinical microbiology,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
January 2012, Advances in experimental medicine and biology,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
December 2011, Emerging infectious diseases,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
September 2011, Emerging infectious diseases,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
January 2014, PloS one,
Aline A de Koeijer, and Thomas J Hagenaars, and Jeroen P G van Leuken, and Arno N Swart, and Gert Jan Boender
January 2012, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,
Copied contents to your clipboard!