[Recovery of vestibulo-ocular reflex in vestibular neuronitis depending on severity of vestibulo-ocular reflex damage]. 2019

V T Pal'chun, and A L Guseva, and E V Baybakova, and A A Makoeva
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia, 117997; Sverzhevsky Research Institute of Clinical Otorhinolaryngology, Moscow, Russia, 117152.

OBJECTIVE The aim of this study is to evaluate clinical symptoms and recovery of vestibule-ocular reflex (VOR) in patients with vestibular neuronitis (VN) in dependence on severity of VOR damage according to video head impulse test (vHIT). METHODS 45 patients with VN and superior or both superior and inferior vestibular nerves involvement were recruited and horizontal gain was measured with vHIT. According to gain asymmetry the patients were divided in three groups: 11 patients with 8-19% gain asymmetry, 10 patients with 20-39% gain asymmetry and 24 patients with more than 40% gain asymmetry. RESULTS Coexisting chronic heart and endocrinological diseases could contribute to greater damage of VOR in VN. In patients with less gain asymmetry the full recovery of gain on the affected side was more often. When gain asymmetry was more than 40%, only 10% of patients demonstrated full recovery of gain in 8-12 months. Dynamic visual acuity (DVA) could normalize in patients with clinically significant gain asymmetry. DVA stays decreased more often in patients with in the most gain asymmetry even after vestibular rehabilitation. Benign paroxysmal positional vertigo appeared in 8.9% of patients with VN and had no correlation with VOR asymmetry. Steroid treatment didn't show significant impact on VOR recovery in patients with VN.

UI MeSH Term Description Entries
D012027 Reflex, Vestibulo-Ocular A reflex wherein impulses are conveyed from the cupulas of the SEMICIRCULAR CANALS and from the OTOLITHIC MEMBRANE of the SACCULE AND UTRICLE via the VESTIBULAR NUCLEI of the BRAIN STEM and the median longitudinal fasciculus to the OCULOMOTOR NERVE nuclei. It functions to maintain a stable retinal image during head rotation by generating appropriate compensatory EYE MOVEMENTS. Vestibulo-Ocular Reflex,Reflex, Vestibuloocular,Reflexes, Vestibo-Ocular,Reflexes, Vestibuloocular,Reflex, Vestibulo Ocular,Reflexes, Vestibo Ocular,Vestibo-Ocular Reflexes,Vestibulo Ocular Reflex,Vestibuloocular Reflex,Vestibuloocular Reflexes
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014792 Visual Acuity Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast. Acuities, Visual,Acuity, Visual,Visual Acuities
D020338 Vestibular Neuronitis Idiopathic inflammation of the VESTIBULAR NERVE, characterized clinically by the acute or subacute onset of VERTIGO; NAUSEA; and imbalance. The COCHLEAR NERVE is typically spared and HEARING LOSS and TINNITUS do not usually occur. Symptoms usually resolve over a period of days to weeks. (Adams et al., Principles of Neurology, 6th ed, p304) Epidemic Neurolabyrinthitis,Neuritis, Vestibular,Neuronitis, Vestibular,Acute Peripheral Vestibulopathy,Acute Vestibular Neuritis,Episodic Recurrent Vertigo,Recurrent Vestibular Neuritis,Recurrent Vestibulopathy,Subacute Vestibular Neuritis,Vestibular Nerve Inflammation,Vestibular Nerve Neuritis,Vestibular Neuritis,Vestibular Neuropathy,Acute Peripheral Vestibulopathies,Acute Vestibular Neuritides,Epidemic Neurolabyrinthitides,Episodic Recurrent Vertigos,Inflammation, Vestibular Nerve,Inflammations, Vestibular Nerve,Nerve Inflammation, Vestibular,Nerve Inflammations, Vestibular,Nerve Neuritides, Vestibular,Nerve Neuritis, Vestibular,Neuritides, Acute Vestibular,Neuritides, Recurrent Vestibular,Neuritides, Subacute Vestibular,Neuritides, Vestibular,Neuritides, Vestibular Nerve,Neuritis, Acute Vestibular,Neuritis, Recurrent Vestibular,Neuritis, Subacute Vestibular,Neuritis, Vestibular Nerve,Neurolabyrinthitides, Epidemic,Neurolabyrinthitis, Epidemic,Neuronitides, Vestibular,Neuropathies, Vestibular,Neuropathy, Vestibular,Peripheral Vestibulopathies, Acute,Peripheral Vestibulopathy, Acute,Recurrent Vertigo, Episodic,Recurrent Vertigos, Episodic,Recurrent Vestibular Neuritides,Recurrent Vestibulopathies,Subacute Vestibular Neuritides,Vertigo, Episodic Recurrent,Vertigos, Episodic Recurrent,Vestibular Nerve Inflammations,Vestibular Nerve Neuritides,Vestibular Neuritides,Vestibular Neuritides, Acute,Vestibular Neuritides, Recurrent,Vestibular Neuritides, Subacute,Vestibular Neuritis, Acute,Vestibular Neuritis, Recurrent,Vestibular Neuritis, Subacute,Vestibular Neuronitides,Vestibular Neuropathies,Vestibulopathies, Acute Peripheral,Vestibulopathies, Recurrent,Vestibulopathy, Acute Peripheral,Vestibulopathy, Recurrent
D064087 Head Impulse Test Identification of SACCADES during a rapid head rotation to assess VESTIBULOOCULAR REFLEX. Head Heave Test,Head Thrust Test,Head Heave Tests,Head Impulse Tests,Head Thrust Tests,Test, Head Heave,Test, Head Impulse,Test, Head Thrust,Tests, Head Heave,Tests, Head Impulse,Tests, Head Thrust
D065635 Benign Paroxysmal Positional Vertigo Idiopathic recurrent VERTIGO associated with POSITIONAL NYSTAGMUS. It is associated with a vestibular loss without other neurological or auditory signs. Unlike in LABYRINTHITIS and VESTIBULAR NEURONITIS, inflammation in the ear is not observed. Benign Recurrent Vertigo,Familial Benign Recurrent Vertigo,Familial Vestibulopathy,Vertigo, Benign Paroxysmal Positional,Vertigo, Benign Recurrent,Vestibulopathy, Familial,Benign Recurrent Vertigos,Familial Vestibulopathies,Recurrent Vertigo, Benign,Recurrent Vertigos, Benign,Vestibulopathies, Familial

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