Lithium carbonate in personality disorders: a case of hysteria. 1977

T van Putten, and J Alban

A growing literature--most uncontrolled--suggests that lithium may be useful in the treatment of some non-manic-depressive personality disorders. The diabolical behavior, conversion symptoms, and diffuse violence and cruelty of a young woman responded remarkably to treatment with lithium. Blind substitution of a placebo confirmed a lithium effect. Patients with the DSM-II diagnosis of explosive, antisocial, and hysterical personalities would appear to be the best candidates for a trial of lithium.

UI MeSH Term Description Entries
D007046 Hysteria Historical term for a chronic, but fluctuating, disorder beginning in early life and characterized by recurrent and multiple somatic complaints not apparently due to physical illness. This diagnosis is not used in contemporary practice. Hysterical Neuroses,Neuroses, Hysterical
D008094 Lithium An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER. Lithium-7,Lithium 7
D010919 Placebos Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol. Sham Treatment
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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