BIOMAT Database Logo BIOMAT Database Logo

Hemagglutinating activity of Dolichos lablab seed protein. 1988

M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brasil.

The hemagglutinating activity of a crude extract and partially purified protein fractions from seeds of Dolichos lablab grown in the state of Bahia, Brazil, has been examined. The crude extract agglutinates rabbit erythrocytes non-specifically with respect to blood groups. The hemagglutination of rabbit erythrocytes induced by the crude extract of D. lablab was inhibited most effectively by N-acetyl-D-glucosamine (3 mM) and alpha-methyl-D-mannoside (3 mM) followed by D-glucosamine (6 mM), D-mannose (6 mM) and D-glucose (12 mM). The spectrum of sugar inhibition of the hemagglutinating activity of the Brazilian seeds combines the characteristics of seeds coming from Turkey and India as indicated by the preferential inhibitory effect exerted by N-acetyl-D-glucosamine and the inhibition by D-mannose and D-glucose. These data suggest that the Brazilian seeds may belong to a different variety of Dolichos lablab.

UI MeSH Term Description Entries
D008766 Methylmannosides Mannosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with methyl alcohol. They include both alpha- and beta-methylmannosides. Methylmannopyranosides
D010940 Plant Proteins Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which PLANT PROTEINS, DIETARY is available. Plant Protein,Protein, Plant,Proteins, Plant
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D002241 Carbohydrates A class of organic compounds composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n. The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrate
D000117 Acetylglucosamine The N-acetyl derivative of glucosamine. Acetyl Glucosamine,N-Acetyl Glucosamine,N-Acetyl-beta-D-Glucosamine,N-Acetylglucosamine,beta-N-Acetylglucosamine,2-Acetamido-2-Deoxy-D-Glucose,2-Acetamido-2-Deoxyglucose,N-Acetyl-D-Glucosamine,2 Acetamido 2 Deoxy D Glucose,2 Acetamido 2 Deoxyglucose,Glucosamine, Acetyl,Glucosamine, N-Acetyl,N Acetyl D Glucosamine,N Acetyl Glucosamine,N Acetyl beta D Glucosamine,N Acetylglucosamine,beta N Acetylglucosamine
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012639 Seeds The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield. Diaspores,Elaiosomes,Embryos, Plant,Plant Embryos,Plant Zygotes,Zygotes, Plant,Diaspore,Elaiosome,Embryo, Plant,Plant Embryo,Plant Zygote,Seed,Zygote, Plant
D037102 Lectins Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition. Animal Lectin,Animal Lectins,Isolectins,Lectin,Isolectin,Lectin, Animal,Lectins, Animal
D037121 Plant Lectins Protein or glycoprotein substances of plant origin that bind to sugar moieties in cell walls or membranes. Some carbohydrate-metabolizing proteins (ENZYMES) from PLANTS also bind to carbohydrates, however they are not considered lectins. Many plant lectins change the physiology of the membrane of BLOOD CELLS to cause agglutination, mitosis, or other biochemical changes. They may play a role in plant defense mechanisms. Lectins, Plant,Phytagglutinin,Plant Agglutinin,Plant Lectin,Agglutinins, Plant,Phytagglutinins,Plant Agglutinins,Agglutinin, Plant,Lectin, Plant

Related Publications

M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Effect of cooking on proteinase inhibitors of Dolichos lablab bean (Dolichos lablab perpureus L.).
September 1995, Plant foods for human nutrition (Dordrecht, Netherlands),
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Expression profiling of the Dolichos lablab lectin during germination and development of the seed.
March 2018, Plant physiology and biochemistry : PPB,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
A new virus disease of Dolichos lablab.
August 1950, Current science,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Purification and characterization of Dolichos lablab lectin.
February 1999, Glycobiology,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Salt tolerance of Rhizobium from Dolichos lablab.
January 1973, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
STUDIES ON PHOSPHATASE FROM LEAVES OF DOLICHOS LABLAB.
July 1963, Bulletin of the Calcutta School of Tropical Medicine,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Triterpene Glycosides from the Seeds of Dolichos lablab.
January 2019, Chemical & pharmaceutical bulletin,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
PARTIAL PURIFICATION OF ACID PHOSPHATASE FROM DOLICHOS LABLAB.
October 1964, Bulletin of the Calcutta School of Tropical Medicine,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Evidence of seed transmission of dolichos yellow mosaic virus, a begomovirus infecting lablab-bean in India.
December 2018, Virusdisease,
M Silva-Lima, and A Pusztai, and D C Nunes, and M E Farias
Aromatic compounds from the seeds of Dolichos lablab L. with anti-inflammatory activity.
December 2023, Fitoterapia,
Copied contents to your clipboard!