Left cerebral cortex complexity differences in sporadic healthy individuals with auditory verbal hallucinations: A pilot study. 2020

Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
Department of Psychiatry, School of Mental Health, Jining Medical University, Jining 272100, Shandong Province, China; Department of Psychiatric-Neuroimaging-Genetics Laboratory (PNG_Lab), Wenzhou Seventh People's Hospital, Wenzhou 325000, Zhejiang Province, China; Department of Psychiatric-Neuroimaging-Genetics and Co-morbidity Laboratory (PNGC_Lab) Tianjin Mental Health Canter, Tianjin Anding Hospital, Mental Health Teaching Hospital of Tianjin Medical University, Tianjin 300222, China. Electronic address: chuanjunzhuotjmh@ieee.org.

In the present pilot study, we aimed to characterize the brain surface differences between 42 sporadic healthy individuals with AVHs (Hi-AVHs) and 50 healthy individuals without AVHs. The Auditory Hallucinations Rating Scale (AHRS) was used to assess the severity of AVHs, while the gyrification index and fractal dimensions were used to evaluate cerebral cortex complexity. We observed a significant increase of the gyrification index was located in the left superior temporal gyrus, the left temporoparietal junction, the left superior frontal gyrus, and the left parietal lobe. The fractal dimensions had significantly increased in the left Wernicke's area, the left Broca's areas and the left parietal lobe. Our pilot findings indicated gyrification index and fractal dimensions differences were only located in the left hemisphere between the groups of Hi-with and without AVHs. However, these differences did not correlate with the AVHs symptoms, and the non-hallucinating healthy individuals did not demonstrate corresponding reverse changes; hence we cannot postulate that cerebral cortex complexity alterations are related to AVHs. Our pilot study provides a clue for further studies aimed at investigating the brain features of Hi-AVHs.

UI MeSH Term Description Entries

Related Publications

Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
December 2020, Brain imaging and behavior,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
November 2011, Schizophrenia research,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
November 2013, Psychological medicine,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
March 2019, Chinese medical journal,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
May 2010, Schizophrenia research,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
March 2011, The Journal of clinical psychiatry,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
March 2002, Journal of psychiatry & neuroscience : JPN,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
March 2022, Translational psychiatry,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
April 2007, Molecular psychiatry,
Chuanjun Zhuo, and Gongying Li, and Ce Chen, and Feng Ji, and Xiao Lin, and Deguo Jiang, and Hongjun Tian, and Lina Wang, and Xiaodong Lin, and Jing Ping
April 2020, The Journal of international medical research,
Copied contents to your clipboard!