Biomaterial Database

Hormonal regulation of fat body glycogen phosphorylase activity in larval Manduca sexta during starvation. 1988

K J Siegert

Freie Universität Berlin, Institut für Tierphysiologie und Angewandte Zoologie, Federal Republic of Germany.

The hormonal regulation of fat body glycogen phosphorylase activity in Manduca sexta larvae was studied. During the first 3 hr of starvation the corpora cardiaca (CC) release a glycogen phosphorylase-activating hormone (GPAH). The haemolymph of 24-hr-starved larvae seems to contain increased levels of GPAH, but after 48 hr the titre can be assumed to be as low as prior to starvation. Abdominal stretch receptors do not appear to be involved in the regulation of GPAH release from the CC. Phosphorylase activation can be prevented by the injection of glucose or by feeding the animals with agar containing various carbohydrates. These treatments seem to prevent the release of GPAH from the CC rather than the action of GPAH on the fat body. The physiological signal which initiates peptide release remains unclear.

UI	MeSH Term	Description	Entries
D007301	Insect Hormones	Hormones secreted by insects. They influence their growth and development. Also synthetic substances that act like insect hormones.	Insect Hormone,Hormone, Insect,Hormones, Insect
D007313	Insecta	Members of the phylum ARTHROPODA composed or organisms characterized by division into three parts: head, thorax, and abdomen. They are the dominant group of animals on earth with several hundred thousand different kinds. Three orders, HEMIPTERA; DIPTERA; and SIPHONAPTERA; are of medical interest in that they cause disease in humans and animals. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p1).	Insects,Insect
D007814	Larva	Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.	Maggots,Tadpoles,Larvae,Maggot,Tadpole
D002241	Carbohydrates	A class of organic compounds composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n. The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES.	Carbohydrate
D004789	Enzyme Activation	Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.	Activation, Enzyme,Activations, Enzyme,Enzyme Activations
D005216	Fat Body	A nutritional reservoir of fatty tissue found mainly in INSECTS and AMPHIBIANS.	Amphibian Fat Body,Insect Fat Body,Amphibian Fat Bodies,Body, Amphibian Fat,Fat Bodies,Fat Bodies, Amphibian,Fat Body, Amphibian,Fat Body, Insect,Insect Fat Bodies
D006005	Phosphorylases	A class of glucosyltransferases that catalyzes the degradation of storage polysaccharides, such as glucose polymers, by phosphorolysis in animals (GLYCOGEN PHOSPHORYLASE) and in plants (STARCH PHOSPHORYLASE).	Glucan Phosphorylase,Phosphorylase,alpha-Glucan Phosphorylases
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia