Four hundred and forty couples were treated by artificial insemination using fresh donor semen. The main indication was azoospermia. The overall pregnancy rate was 84.9% resulting in 287 take-home babies. The rate of ectopic pregnancies, perinatal deaths and spontaneous abortions were comparable to the general population. The accumulating pregnancy rate within 5 months was 86.8. Women older than 35 years had similar pregnancy rates than younger patients. Socioeconomic class, length of infertility and ovulatory disturbances either before or during treatment affected significantly the pregnancy rates.