BIOMAT Database Logo BIOMAT Database Logo

Mammalian Pericardium-Based Bioprosthetic Materials in Xenotransplantation and Tissue Engineering. 2020

Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, Moscow, 119991, Russia.

Bioprosthetic materials based on mammalian pericardium tissue are the gold standard in reconstructive surgery. Their application range covers repair of rectovaginal septum defects, abdominoplastics, urethroplasty, duraplastics, maxillofacial, ophthalmic, thoracic and cardiovascular reconstruction, etc. However, a number of factors contribute to the success of their integration into the host tissue including structural organization, mechanical strength, biocompatibility, immunogenicity, surface chemistry, and biodegradability. In order to improve the material's properties, various strategies are developed, such as decellularization, crosslinking, and detoxification. In this review, the existing issues and long-term achievements in the development of bioprosthetic materials based on the mammalian pericardium tissue, aimed at a wide-spectrum application in reconstructive surgery are analyzed. The basic technical approaches to preparation of biocompatible forms providing continuous functioning, optimization of biomechanical and functional properties, and clinical applicability are described.

UI MeSH Term Description Entries
D008322 Mammals Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young. Mammalia,Mammal
D010496 Pericardium A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers. Epicardium,Fibrous Pericardium,Parietal Pericardium,Pericardial Cavity,Pericardial Space,Serous Pericardium,Visceral Pericardium,Cavities, Pericardial,Cavity, Pericardial,Pericardial Cavities,Pericardial Spaces,Pericardium, Fibrous,Pericardium, Parietal,Pericardium, Serous,Pericardium, Visceral,Pericardiums, Fibrous,Pericardiums, Serous,Serous Pericardiums,Space, Pericardial,Spaces, Pericardial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001672 Biocompatible Materials Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. Biomaterials,Bioartificial Materials,Hemocompatible Materials,Bioartificial Material,Biocompatible Material,Biomaterial,Hemocompatible Material,Material, Bioartificial,Material, Biocompatible,Material, Hemocompatible
D014183 Transplantation, Heterologous Transplantation between animals of different species. Xenotransplantation,Heterograft Transplantation,Heterografting,Heterologous Transplantation,Xenograft Transplantation,Xenografting,Transplantation, Heterograft,Transplantation, Xenograft
D019736 Prostheses and Implants Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally. Implants, Artificial,Prostheses and Implant,Prosthesis,Prosthetic Implant,Endoprostheses,Endoprosthesis,Prostheses,Prosthetic Implants,Artificial Implant,Artificial Implants,Implant and Prostheses,Implant, Artificial,Implant, Prosthetic,Implants and Prostheses,Implants, Prosthetic
D023822 Tissue Engineering Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures. Engineering, Tissue

Related Publications

Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
RGD-modified acellular bovine pericardium as a bioprosthetic scaffold for tissue engineering.
November 2009, Journal of materials science. Materials in medicine,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Cardiac xenotransplantation technology provides materials for improved bioprosthetic heart valves.
July 2011, The Journal of thoracic and cardiovascular surgery,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Cardiac xenotransplantation technology provides materials for improved bioprosthetic heart valves.
January 2011, The Journal of thoracic and cardiovascular surgery,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Gelatin-Based Materials in Ocular Tissue Engineering.
April 2014, Materials (Basel, Switzerland),
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Silk-Based Materials for Hard Tissue Engineering.
February 2021, Materials (Basel, Switzerland),
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Protein-based materials in load-bearing tissue-engineering applications.
January 2014, Regenerative medicine,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Protein-Based Hydrogels: Promising Materials for Tissue Engineering.
February 2022, Polymers,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Cellulose-based scaffold materials for cartilage tissue engineering.
July 2006, Biomaterials,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Peptide-Based Hydrogels: Template Materials for Tissue Engineering.
April 2023, Journal of functional biomaterials,
Ekaterina A Grebenik, and Elvira R Gafarova, and Leonid P Istranov, and Elena V Istranova, and Xiaowei Ma, and Jing Xu, and Weisheng Guo, and Anthony Atala, and Peter S Timashev
Chitin-based materials in tissue engineering: applications in soft tissue and epithelial organ.
January 2011, International journal of molecular sciences,
Copied contents to your clipboard!