Umbilical artery Doppler flow velocity waveform: the outcome of pregnancies with absent end diastolic flow. 1988

F D Johnstone, and N G Haddad, and P Hoskins, and W McDicken, and S Chambers, and B Muir
Department of Obstetrics, Simpson Memorial Maternity Pavilion, Royal Infirmary, Edinburgh, Scotland.

We have studied doppler recordings of flow velocity waveform of the umbilical artery in 380 high-risk pregnancies and 160 patients with uncomplicated pregnancies. The results were not used in clinical management. In 24 cases, all in high-risk pregnancies, there was absence of end diastolic flow (AEDF). Four babies died, 22 out of 24 weighted less than the 5th centile for gestation and 20 were delivered by Caesarean Section. With only four exceptions, all fetuses showed other evidence of antenatal fetal compromise, though this was delayed in some cases for up to 24 days. AEDF does not appear to prejudice neonatal outcome. All six babies born weighing 750-999 g survived. In addition, 4 patients continued their pregnancy for 3-6 weeks after the first doppler with AEDF. Only one of the 4 developed other evidence of fetal compromise and two had vaginal deliveries. In our experience, AEDF is found only in abnormal pregnancy, and is a very serious sign of likely fetal compromise. It is an indication for extremely careful surveillance but not necessarily an indication for delivery.

UI MeSH Term Description Entries
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011256 Pregnancy Outcome Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; or SPONTANEOUS ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO. Outcome, Pregnancy,Outcomes, Pregnancy,Pregnancy Outcomes
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D005260 Female Females
D005323 Fetal Monitoring Physiologic or biochemical monitoring of the fetus. It is usually done during LABOR, OBSTETRIC and may be performed in conjunction with the monitoring of uterine activity. It may also be performed prenatally as when the mother is undergoing surgery. Monitoring, Fetal,Fetal Monitorings,Monitorings, Fetal
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014465 Ultrasonics A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues. Ultrasonic
D014469 Umbilical Arteries Specialized arterial vessels in the umbilical cord. They carry waste and deoxygenated blood from the FETUS to the mother via the PLACENTA. In humans, there are usually two umbilical arteries but sometimes one. Arteries, Umbilical,Artery, Umbilical,Umbilical Artery

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