BIOMAT Database Logo BIOMAT Database Logo

Lysobactin, a novel antibacterial agent produced by Lysobacter sp. I. Taxonomy, isolation and partial characterization. 1988

J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Squibb Institute for Medical Research, Princeton, New Jersey 08543-4000.

A new antibacterial agent, lysobactin, has been isolated from a species of Lysobacter (ATCC 53042). The antibiotic was recovered from the Lysobacter cell mass by extraction and reversed phase chromatography. Lysobactin is a dibasic peptide with marked activity against Gram-positive aerobic and anaerobic bacteria.

UI MeSH Term Description Entries
D009842 Oligopeptides Peptides composed of between two and twelve amino acids. Oligopeptide
D005285 Fermentation Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID. Fermentations
D006090 Gram-Negative Bacteria Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method. Gram Negative Bacteria
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D047630 Depsipeptides Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized. Cyclic Depsipeptide,Cyclodepsipeptide,Depsipeptide,Peptolide,Peptolides,Cryptophycins,Cyclodepsipeptides,Depsipeptides, Cyclic,Cyclic Depsipeptides,Depsipeptide, Cyclic

Related Publications

J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Lysobactin, a novel antibacterial agent produced by Lysobacter sp. II. Biological properties.
December 1988, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Tripropeptins, novel antimicrobial agents produced by Lysobacter sp. I. Taxonomy, isolation and biological activities.
December 2001, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Gualamycin, a novel acaricide produced by Streptomyces sp. NK11687. I. Taxonomy, production, isolation, and preliminary characterization.
July 1995, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Stachybocins, novel endothelin receptor antagonists, produced by Stachybotrys sp. M6222. I. Taxonomy, fermentation, isolation and characterization.
December 1995, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Pironetin, a novel plant growth regulator produced by Streptomyces sp. NK10958. I. Taxonomy, production, isolation and preliminary characterization.
June 1994, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Novel amino acid metabolite produced by Streptomyces sp.: I. Taxonomy, isolation, and structural elucidation.
June 1997, Bioscience, biotechnology, and biochemistry,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Okilactomycin, a novel antibiotic produced by a Streptomyces species. I. Taxonomy, fermentation, isolation and characterization.
November 1987, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. I. Taxonomy, production, isolation and biological activity.
December 1992, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Radamycin, a novel thiopeptide produced by streptomyces sp. RSP9. I. Taxonomy, fermentation, isolation and biological activities.
April 2002, The Journal of antibiotics,
J O'Sullivan, and J E McCullough, and A A Tymiak, and D R Kirsch, and W H Trejo, and P A Principe
Purification and partial characterization of a novel antibacterial agent (Bac1829) Produced by Staphylococcus aureus KSI1829.
September 1996, Applied and environmental microbiology,
Copied contents to your clipboard!