Organ Doses, Effective Dose, and Cancer Risk From Coronary CT Angiography Examinations. 2020

Maede Mahmoodi, and Ali Chaparian
Medical Physics Department, Isfahan University of Medical Sciences, Isfahan, Iran.

OBJECTIVE. The purposes of this study were to determine organ and effective doses and to estimate the risk of exposure-induced cancer death (REID) associated with coronary CT angiography (CCTA) examinations. SUBJECTS AND METHODS. CCTA examinations were performed in three stages: calcium score, monitoring, and cardiac phases for all patients. Effective dose was calculated using two methods. The first was based on the scanner-derived dose-length product, and the second entailed use of an organ and effective dose calculator software application. Organ doses were calculated on the basis of the tissue weighting factors of International Commission on Radiation Protection report 103. REID values were assessed with a cancer risk estimator software application. RESULTS. The study included 185 patients (95 men, 90 women). For women, breast doses were high at 52.04 ± 14.08 mGy. The mean effective dose in the women was greater than that in the men (24.05 vs 16.30 mSv, p < 0.05). The mean REID values in patients undergoing CCTA with a 64-MDCT scanner were 13.4 per 10,000 men (1 in 746) and 19.6 per 10,000 women (1 in 508). The REID values were considerably higher for the younger women. CONCLUSION. The results of this study will help referring physicians justify requesting CCTA examinations by considering their benefits for diagnosis on the one hand and awareness of the risk of radiation-induced cancer on the other. In the case of CCTA scans that are properly justified by clinical indication, patients and physicians should not be concerned about the radiation risks.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009381 Neoplasms, Radiation-Induced Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation. Radiation-Induced Cancer,Cancer, Radiation-Induced,Radiation-Induced Neoplasms,Cancer, Radiation Induced,Cancers, Radiation-Induced,Neoplasm, Radiation-Induced,Neoplasms, Radiation Induced,Radiation Induced Cancer,Radiation Induced Neoplasms,Radiation-Induced Cancers,Radiation-Induced Neoplasm
D011829 Radiation Dosage The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv). Sievert Units,Dosage, Radiation,Gray Units,Gy Radiation,Sv Radiation Dose Equivalent,Dosages, Radiation,Radiation Dosages,Units, Gray,Units, Sievert
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072226 Computed Tomography Angiography A non-invasive method that uses a CT scanner for capturing images of blood vessels and tissues. A CONTRAST MATERIAL is injected, which helps produce detailed images that aid in diagnosing VASCULAR DISEASES. Angiography, CT,Angiography, Computed Tomography,CT Angiography,Angiographies, CT,Angiographies, Computed Tomography,CT Angiographies,Computed Tomography Angiographies,Tomography Angiographies, Computed,Tomography Angiography, Computed
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old

Related Publications

Maede Mahmoodi, and Ali Chaparian
January 2023, European journal of radiology,
Maede Mahmoodi, and Ali Chaparian
May 2005, Journal de radiologie,
Maede Mahmoodi, and Ali Chaparian
January 1987, AJR. American journal of roentgenology,
Maede Mahmoodi, and Ali Chaparian
November 2020, Radiation protection dosimetry,
Maede Mahmoodi, and Ali Chaparian
December 2015, Radiation protection dosimetry,
Maede Mahmoodi, and Ali Chaparian
May 1996, The British journal of radiology,
Maede Mahmoodi, and Ali Chaparian
August 2006, Journal of applied clinical medical physics,
Maede Mahmoodi, and Ali Chaparian
January 2009, The British journal of radiology,
Maede Mahmoodi, and Ali Chaparian
June 2018, Radiation protection dosimetry,
Copied contents to your clipboard!