Biomaterial Database

[Effect of stimulation of the central gray matter of the midbrain on responses of neurons of the ventroposteromedial nucleus of the thalamus in cats]. 1988

E V Gura, and V V Garkavenko

Effect of the midbrain central gray matter (CGM) stimulation on neuronal responses of the thalamic ventro-postero-medial (VPM) nucleus evoked by stimulation of the tooth pulp, A-alpha, A-delta fibres of the infraorbital nerve and caudal nucleus of the spinal trigeminal tract have been studied in cats under thiopental-chloralose anesthesia. It is shown that the CGM stimulation by a short train of stimuli evoked excitatory responses with a latency of 30 ms in part of investigated neurons. The conditioning CGM stimulation suppressed responses in neurons of "low-threshold", "convergent" and "high-threshold" groups. Responses induced by stimulation of the tooth pulp and A-delta fibres of the infraorbital nerve in 40% of neurons and by stimulation of the A-alpha fibres of the infraorbital nerve in about 26% of investigated thalamic neurons were completely suppressed. The inhibitory influence of the CGM stimulation on neuronal responses evoked by stimulation of peripheral nerves and caudal nucleus of the spinal trigeminal tract shows that the CGM influences directly the activity of thalamic neurons.

UI	MeSH Term	Description	Entries
D008636	Mesencephalon	The middle of the three primitive cerebral vesicles of the embryonic brain. Without further subdivision, midbrain develops into a short, constricted portion connecting the PONS and the DIENCEPHALON. Midbrain contains two major parts, the dorsal TECTUM MESENCEPHALI and the ventral TEGMENTUM MESENCEPHALI, housing components of auditory, visual, and other sensorimoter systems.	Midbrain,Mesencephalons,Midbrains
D009474	Neurons	The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.	Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013787	Thalamic Nuclei	Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.	Nuclei, Thalamic