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The psychophysiological effects of aging in mice of the line F1 (C57BL/6×DBA/2) at the age of 3, 7, and 14 months were investigated. It was found that the cognitive abilities, memory and spatial orientation in all animals did not depend on age, they were able to form a 4-link food-getting habit. The instability of behavior found in all mice at the stereotyped stage of in the form of periodic reproduction of false and irrational realizations was determined by the peculiarities of the basic nervous processes - increased excitability and weakness of inhibition. It was possible to establish that the consistent reduction of the excitation phase during the aging process caused the instability of the dominant state and motivational activity, negatively affecting the attention stable and, consequently, the ability to consistently reproduce the optimal variant of habit.
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
March 2016,
Veterinary pathology,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
August 1978,
Cancer research,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
January 1988,
Eksperimental'naia onkologiia,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
March 2001,
Experimental biology and medicine (Maywood, N.J.),
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
March 1995,
Cellular immunology,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
October 1982,
Experimental hematology,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
January 1993,
Journal of applied toxicology : JAT,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
January 1974,
International archives of allergy and applied immunology,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
October 1984,
Brain research bulletin,
K A Nikolskaya, and
V V Tolchennikova, and
M V Kondashevskaya
August 1982,
Brain research,
