Cherubism is a benign hereditary giant-cell lesion of the mandibular and maxillary spongiosa which appears during childhood between 2 and 5 years old and progresses until puberty when it spontaneously regresses. It appears under the form of a bilateral painless swelling. It normally requires no treatment. Three children of a same algerian family who suffered from this disease were brought into our ward. Radiographic examinations were realized among which scanner allowed the establishment of a good definition of the lesions. The 3 patients were finally operated, the surgical intervention having been effectively necessary.