Biomaterial Database

Risk factors for breast cancer and their prognostic significance. 1988

M Ewertz

Danish Cancer Registry, Institute of Cancer Epidemiology Under the Danish Cancer Society, Copenhagen, Denmark.

Since 1960 a 50% increase has occurred in breast cancer incidence in Denmark. With the present rates one out of fifteen Danish women will develop breast cancer before the age of 75 years. To evaluate the influence of known and suspected epidemiologic factors on the risk of developing breast cancer and on prognosis, a population-based study has been carried out, where cases were identified from the files of the Danish Breast Cancer Cooperative Group (DBCG) and the Danish Cancer Registry. Results are communicated from the case-control part of this study, including 1486 breast cancer cases aged less than 70, diagnosed over a one-year period, and an age-stratified-random sample of 1336 women without breast cancer from the general population. Data on risk factors were collected by self-administered (mailed) questionnaires. Classical risk factors, such as high social status, nulliparity, early menarche and late natural menopause were confirmed, while no association was found between breast cancer and maternal age at first childbirth.

UI	MeSH Term	Description	Entries
D008423	Maternal Age	The age of the mother in PREGNANCY.	Age, Maternal,Ages, Maternal,Maternal Ages
D008572	Menarche	The first MENSTRUAL CYCLE marked by the initiation of MENSTRUATION.
D008593	Menopause	The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.	Change of Life, Female
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D001943	Breast Neoplasms	Tumors or cancer of the human BREAST.	Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D003718	Denmark	A country in northern Europe, bordering the Baltic Sea and the North Sea. The capital is Copenhagen.	Faeroe Islands,Faroe Islands
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly