[CT evaluation of cerebellar atrophy with aging in healthy persons]. 1988

J Nishimiya
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.

The author studied the incidence of computed tomographic evidences of cerebellar atrophy in 2,102 neurologically normal subjects. The subjects were selected from approximately 10,000 cases who underwent CT examination at Juntendo University hospital since April 17, 1978 to October 30, 1979. The 2,102 subjects were classified into 10 groups according to their age, as following: 1) below the age of 1 year, 2) between 1 and 4 years, 3) between 5 and 9 years, 4) second decade, 5) third decade, 6) fourth decade, 7) fifth decade, 8) sixth decade, 9) seventh decade, 10) after the age of seventy. The incidence of enlarged cerebellar vermis fissures, cerebellar hemispheric fissures, subarachnoid space around the cerebellum and the fourth ventricle were explored on CT. As regards the fourth ventricle, the maximum transverse width of the fourth ventricle and the maximum inside diameter of the posterior fossa were measured on CT, and ratio of the width of the fourth ventricle against the diameter of the posterior fossa were calculated. Statistical analysis was performed using chi 2 test or t test in each age group. The results obtained were as following: I. The incidence of enlarged cerebellar vermis fissures and cerebellar hemispheric fissures increased gradually with aging. Though the difference were almost significant in any groups older than 20 years. It was noteworthy among those who were older than 60 years. II. The incidence of enlarged subarachnoid space around the cerebellum also increased significantly after the age of sixty, III. In subjects older than twenty, the width of the fourth ventricle increased with aging.(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002531 Cerebellum The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills. Cerebella,Corpus Cerebelli,Parencephalon,Cerebellums,Parencephalons
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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