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A double-blind trial of the effects of vitamin C on the frequency, severity and duration of post-suxamethonium pains was performed. Fifty-three patients undergone bronchoscopy received either a placebo or 10 g of vitamin C. No beneficial effect was demonstrated. In 18 patients no relationship was found between pre-anaesthetic buffy layer vitamin C levels and the subsequent pains. Measurement of buffy layer and plasma vitamin C levels before and after anaesthesia did not suggest that vitamin C deficiency occurs during or immediately after administration of suxamethonium. It is concluded that the administration of vitamin C cannot be recommended as a means for prevention of suxamethonium pains.
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
October 1971,
Anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
December 1975,
British journal of anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
February 1982,
Middle East journal of anaesthesiology,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
April 1972,
Anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
October 1979,
Anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
February 1975,
Proceedings of the Royal Society of Medicine,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
February 1980,
British journal of anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
July 1971,
British journal of anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
April 1971,
Anaesthesia,
J B Wood, and
E C Attwood, and
B M Wood, and
R M Dowling, and
F Bradley
January 1961,
British journal of anaesthesia,
