Zoledronic acid for the treatment of pregnancy-associated femoral head necrosis: A case report. 2020

Estella Musacchio, and Leonardo Sartori
Department of Medicine DIMED, Clinica Medica 1, University of Padova, via Giustiniani 2, 35128 Padova, Italy.

BACKGROUND The management of pregnancy-associated femoral necrosis is controversial. Conservative management may eventually lead to hip replacement. METHODS A 40-year-old woman developed necrosis of the left hip during her first pregnancy. Treatment with zoledronic acid three months after delivery resulted in rapid reduction of the necrotic area. The patient's second pregnancy shortly afterwards had no complications. A magnetic resonance scan three years later documented complete resolution. CONCLUSIONS Femoral head necrosis should be suspected in the differential diagnosis of pain in pregnancy. Zoledronic acid given in the early stages prevented progression to hip arthritis in this case.

UI MeSH Term Description Entries

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