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Serial serum samples from 39 renal allograft recipients were screened for cold and warm cytotoxic antibodies before and after grafting. In the group of patients who developed antibodies only after grafting, 6 had cytotoxins reactive at 37 degree C and 5 had cytotoxins reactive at 15 degree. At one year, all the patients with cold alloantibodies has functioning grafts, but none of the patients with warm antibodies had kept their graft. In three patients with cold antibodies, the cytotoxins reacted with a subpopulation of cells enriched in B lymphocytes but not with T cells eluted from nylon wool columns. This suggests that certain kinds of antibodies which appear in the blood after grafting may have enhancing properties.
R Roy, and
J G Lachance, and
F Daguillard
January 2002,
American journal of nephrology,
R Roy, and
J G Lachance, and
F Daguillard
January 1990,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
R Roy, and
J G Lachance, and
F Daguillard
April 1976,
Lancet (London, England),
R Roy, and
J G Lachance, and
F Daguillard
January 1982,
Transfusion,
R Roy, and
J G Lachance, and
F Daguillard
January 1987,
Acta medica Iugoslavica,
R Roy, and
J G Lachance, and
F Daguillard
August 2018,
Pediatric transplantation,
R Roy, and
J G Lachance, and
F Daguillard
January 2017,
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia,
R Roy, and
J G Lachance, and
F Daguillard
November 2002,
Transplantation proceedings,
R Roy, and
J G Lachance, and
F Daguillard
February 1987,
Transplantation proceedings,
R Roy, and
J G Lachance, and
F Daguillard
February 2018,
Transplant immunology,
