Probe-label-free electrochemical aptasensor based on methylene blue-anchored graphene oxide amplification. 2013

Jing Rong Chen, and Xiao Xia Jiao, and Hong Qun Luo, and Nian Bing Li
Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. linb@swu.edu.cn luohq@swu.edu.cn.

Two novel probe-label-free electrochemical aptasensors based on methylene blue (MB)-anchored graphene oxide (GO) amplification were developed for thrombin (TB) and ATP detection, taking advantage of the specific binding affinity of the aptamer towards the target and the different affinities of GO for MB, ssDNA, dsDNA, and G-quadruplex.

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