A mini mass spectrometer with a low noise Faraday detector. 2020

Yang Tang, and Qian Xu, and Dayu Li, and Wei Xu
School of Life Science, Beijing Institute of Technology, Beijing 100081, China. weixu@bit.edu.cn.

An ion trap mass spectrometer is conventionally featured with an electron multiplier as its detector. However, an electron multiplier can typically work at pressures below 20 mTorr with a high voltage applied, which limits the further miniaturization of ion trap mass spectrometers. In this work, a low noise Faraday detector was developed and integrated in our miniature mass spectrometer instrument, and a post data processing method was applied to improve its performance. A limit of detection of 1 ng mL-1 was achieved, and quantitation performance and mass resolution were characterized. This technology could be useful in the further development of miniature mass spectrometers by increasing background pressures.

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