-transparent.png){kind=logo}
Protection from carbon tetrachloride (CCL4)-induced hepatotoxicity by protein A was assessed histologically in rats. Carbon tetrachloride exposure produced swollen, vacuolated and necrotic cells in the centrilobular region of the hepatocyte in rats. Animals given protein A prior to and during CCL1 treatment showed a complete absence of hepatic lesions. Our study showed that protein A, a potent immunomodulator, has the potential to reduce liver injury caused by carbon tetrachloride, a known hepatotoxin in the rat.
Related Publications
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
January 1975,
Drug metabolism and disposition: the biological fate of chemicals,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
January 1975,
Toxicology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
April 1987,
Experimental and molecular pathology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
September 2007,
Journal of ethnopharmacology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
January 1981,
Gastroenterologia Japonica,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
January 2018,
Journal of basic and clinical physiology and pharmacology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
February 1990,
Research communications in chemical pathology and pharmacology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
October 1979,
Toxicology and applied pharmacology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
May 1994,
Research communications in chemical pathology and pharmacology,
K P Singh, and
A K Saxena, and
S I Zaidi, and
P D Dwivedi, and
S P Srivastava, and
P K Seth, and
P K Ray
April 1982,
Experientia,
