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131I labelled F (ab')2 fragments of monoclonal antibodies against CA 19-9 and CEA ("radioimmunococktail" IMACIS 1) were used in a prospective study (n = 60 patients) and in a retrospective study (n = 32 patients) for the detection of colorectal carcinomas (n = 67) and other gastrointestinal CEA/CA 19-9-producing tumors (n = 32). Sensitivity was 82% and specificity 90%. Immunoscintigraphy proved useful and complementary to CT scan and sonography, especially in the diagnosis of pelvic recurrences and intra-abdominal metastases. In addition, monoclonal antibody OC 125 (IMACIS 2) was used for the detection of ovarian carcinomas (n = 10) and other CA 125 producing tumors. Immunoscintigraphy was positive in all patients (n = 18) suggesting that this radioimmunological approach could be of use in the staging, therapeutic control and earlier diagnosis of recurrent epithelial ovarian carcinoma.
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J Spitz, and
G Hör
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June 1989,
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December 1985,
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R P Baum, and
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February 1989,
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R P Baum, and
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M Albrecht, and
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January 2013,
Archives of gynecology and obstetrics,
R P Baum, and
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G Hör
August 1991,
Geburtshilfe und Frauenheilkunde,
R P Baum, and
M Lorenz, and
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M Albrecht, and
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A Hertel, and
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G Hör
May 1988,
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R P Baum, and
M Lorenz, and
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M Albrecht, and
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A Hertel, and
J Spitz, and
G Hör
December 1984,
Nihon Gan Chiryo Gakkai shi,
R P Baum, and
M Lorenz, and
C Hottenrott, and
M Albrecht, and
R Senekowitsch, and
J Happ, and
A Hertel, and
J Spitz, and
G Hör
September 2023,
Sensors (Basel, Switzerland),
R P Baum, and
M Lorenz, and
C Hottenrott, and
M Albrecht, and
R Senekowitsch, and
J Happ, and
A Hertel, and
J Spitz, and
G Hör
January 1986,
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