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NCCN Guidelines Insights: Primary Cutaneous Lymphomas, Version 2.2020. 2020
Neha Mehta-Shah, and
Steven M Horwitz, and
Stephen Ansell, and
Weiyun Z Ai, and
Jeffrey Barnes, and
Stefan K Barta, and
Mark W Clemens, and
Ahmet Dogan, and
Kristopher Fisher, and
Aaron M Goodman, and
Gaurav Goyal, and
Joan Guitart, and
Ahmad Halwani, and
Bradley M Haverkos, and
Richard T Hoppe, and
Eric Jacobsen, and
Deepa Jagadeesh, and
Matthew A Lunning, and
Amitkumar Mehta, and
Elise A Olsen, and
Barbara Pro, and
Saurabh A Rajguru, and
Satish Shanbhag, and
Aaron Shaver, and
Andrei Shustov, and
Lubomir Sokol, and
Pallawi Torka, and
Carlos Torres-Cabala, and
Ryan Wilcox, and
Basem M William, and
Jasmine Zain, and
Mary A Dwyer, and
Hema Sundar, and
Youn H Kim
Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma (CTCL), and Sézary syndrome (SS) is a rare erythrodermic and leukemic subtype of CTCL characterized by significant blood involvement. Although early-stage disease can be effectively treated predominantly with skin-directed therapies, systemic therapy is often necessary for the treatment of advanced-stage disease. Systemic therapy options have evolved in recent years with the approval of novel agents such as romidepsin, brentuximab vedotin, and mogamulizumab. These NCCN Guidelines Insights discuss the diagnosis and management of MF and SS (with a focus on systemic therapy).
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