BIOMAT Database Logo BIOMAT Database Logo

A new look at erythromycin. 1977

R W Lacey

This article reviews the current place of erythromycin in antibiotic therapy. Overall, erythromycin is thought to be underused because: (1) the fear of resistance has been exaggerated; (2) significant toxicity has been associated with only one derivative (the estolate); (3) newer antibiotics have very rarely been demonstrated to be superior to erythromycin. Erythromycin has an important place in treating acute upper and lower respiratory tract infections, acute otitis media, sinusitis, skin and soft tissue, osteomyelitis, prostatitis, infections due to Mycoplasma spp. and Chlamydia organisms, and infections due to anaerobes.

UI MeSH Term Description Entries
D008297 Male Males
D010019 Osteomyelitis INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA. Osteomyelitides
D012141 Respiratory Tract Infections Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases. Respiratory System Infections,Upper Respiratory Tract Infection,Upper Respiratory Tract Infections,Infections, Respiratory,Infections, Respiratory Tract,Infections, Upper Respiratory,Infections, Upper Respiratory Tract,Respiratory Infections,Upper Respiratory Infections,Infection, Respiratory System,Infection, Respiratory Tract,Respiratory Infection, Upper,Respiratory System Infection,Respiratory Tract Infection
D004352 Drug Resistance, Microbial The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS). Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D004917 Erythromycin A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. Erycette,Erymax,Erythromycin A,Erythromycin C,Erythromycin Lactate,Erythromycin Phosphate,Ilotycin,T-Stat,Lactate, Erythromycin,Phosphate, Erythromycin,T Stat,TStat
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001424 Bacterial Infections Infections by bacteria, general or unspecified. Bacterial Disease,Bacterial Infection,Infection, Bacterial,Infections, Bacterial,Bacterial Diseases
D012874 Skin Diseases, Infectious Skin diseases caused by bacteria, fungi, parasites, or viruses. Infectious Skin Diseases,Disease, Infectious Skin,Diseases, Infectious Skin,Infectious Skin Disease,Skin Disease, Infectious
D014570 Urologic Diseases Pathological processes of the URINARY TRACT in both males and females. Urinary Tract Diseases,Urological Diseases,Disease, Urinary Tract,Disease, Urologic,Disease, Urological,Diseases, Urinary Tract,Diseases, Urologic,Diseases, Urological,Urinary Tract Disease,Urologic Disease,Urological Disease

Related Publications

R W Lacey
Another look at erythromycin.
July 1978, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
R W Lacey
Another look at erythromycin.
April 1978, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
R W Lacey
A NEW LOOK AT RUBELLA.
November 1963, British medical journal,
R W Lacey
A new look at smoking.
September 1982, American pharmacy,
R W Lacey
[A new look at selenium].
December 1985, Harefuah,
R W Lacey
A new look at biosimilarity.
January 1977, Biorheology,
R W Lacey
A new look at strokes.
October 1969, Nursing mirror and midwives journal,
R W Lacey
A new look at sanitation.
January 1949, American journal of public health and the nation's health,
R W Lacey
A new look at measles.
March 1992, Infectious disease clinics of North America,
R W Lacey
A new look at couriers.
January 1976, Frontier Nursing Service quarterly bulletin,
Copied contents to your clipboard!