Carotid endarterectomy: prevention of stroke in asymptomatic (stage I) and symptomatic (stage II) patients? 1988

H Hamann
Department of Vascular, Thoracic and Cardiac Surgery, University of Ulm, FRG.

This paper reports on 1097 carotid artery operations (651 in stage I and 446 in stage II of cerebrovascular insufficiency) carried out from 1970 to 1988. The indication for surgery was based on the following criteria: hemodynamic efficacy of the stenosis, risk of embolism of the vascular lesion, causal connection between the extracranial stenosis and the neurological deficit, and exclusion of a serious concomitant internal disease. As operation technique, open thrombendarterectomy using an intraluminal shunt was applied. The arteriotomy was closed by means of a patch. When there was a simultaneous elongation of the internal carotid artery (kinking), the internal was shortened with reinsertion into the common carotid artery. In stage I the surgical mortality was 0.9%, and the surgical morbidity (cerebrovascular deficit of ischemic origin) was 1.2%; in stage II the corresponding figures were 1.2% and 2.4% respectively. The period of follow-up observation comprised three to 207 months (up to 17 years) with an average value of 70 months for patients of stage I and 67 months for patients of stage II. Patients of stage I suffered a stroke in 1.4% (n = 9) and patients in stage II suffered a stroke in 2.4% (n = 10) of cases i.e. annually 0.2% in stage I and 0.3% in stage II. There have been various reports on the favorable spontaneous course of patients with carotid stenoses treated non-surgically. A risk of stroke of 1% to 3% was reported for stage I and a risk of stroke of 3% to 4% was reported for stage II.(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D002341 Carotid Artery Thrombosis Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX. Thrombosis, Carotid Artery,Carotid Thrombosis,Common Carotid Artery Thrombosis,External Carotid Artery Thrombosis,Internal Carotid Artery Thrombosis,Thrombosis, Carotid,Thrombosis, Common Carotid Artery,Thrombosis, External Carotid Artery,Thrombosis, Internal Carotid Artery,Carotid Artery Thromboses
D002343 Carotid Artery, Internal Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose. Arteries, Internal Carotid,Artery, Internal Carotid,Carotid Arteries, Internal,Internal Carotid Arteries,Internal Carotid Artery
D002544 Cerebral Infarction The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction). Anterior Choroidal Artery Infarction,Cerebral Infarct,Infarction, Cerebral,Posterior Choroidal Artery Infarction,Subcortical Infarction,Cerebral Infarction, Left Hemisphere,Cerebral Infarction, Right Hemisphere,Cerebral, Left Hemisphere, Infarction,Cerebral, Right Hemisphere, Infarction,Infarction, Cerebral, Left Hemisphere,Infarction, Cerebral, Right Hemisphere,Infarction, Left Hemisphere, Cerebral,Infarction, Right Hemisphere, Cerebral,Left Hemisphere, Cerebral Infarction,Left Hemisphere, Infarction, Cerebral,Right Hemisphere, Cerebral Infarction,Right Hemisphere, Infarction, Cerebral,Cerebral Infarctions,Cerebral Infarcts,Infarct, Cerebral,Infarction, Subcortical,Infarctions, Cerebral,Infarctions, Subcortical,Infarcts, Cerebral,Subcortical Infarctions
D003251 Constriction, Pathologic The condition of an anatomical structure's being constricted beyond normal dimensions. Stenosis,Stricture,Constriction, Pathological,Pathologic Constriction,Constrictions, Pathologic,Pathologic Constrictions,Pathological Constriction,Stenoses,Strictures
D004691 Endarterectomy Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY. Thromboendarterectomy,Endarterectomies,Thromboendarterectomies
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup

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