[Lipoatrophic diabetes with insulin resistance controlled by metformin].
1988
B Labeille, and
J D Lalau, and
L Chouquais, and
X Debussche, and
L Terminassian, and
J Quichaud, and
J P Denoeux
Service de Dermatologie et Vénéréologie, CHRU Amiens, Hôpital Sud.
UI
MeSH Term
Description
Entries
D007333
Insulin Resistance
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
A type of diabetes mellitus that is characterized by severe INSULIN RESISTANCE and LIPODYSTROPHY. The latter may be generalized, partial, acquired, or congenital (LIPODYSTROPHY, CONGENITAL GENERALIZED).