-transparent.png){kind=logo}
Characterizing Environmental Surveillance Sites in Nigeria and Their Sensitivity to Detect Poliovirus and Other Enteroviruses. 2022
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
World Health Organization Nigeria, Abuja, Federal Capital Territory (FCT), Nigeria.
Environmental surveillance (ES) for poliovirus is increasingly important for polio eradication, often detecting circulating virus before paralytic cases are reported. The sensitivity of ES depends on appropriate selection of sampling sites, which is difficult in low-income countries with informal sewage networks. We measured ES site and sample characteristics in Nigeria during June 2018-May 2019, including sewage physicochemical properties, using a water-quality probe, flow volume, catchment population, and local facilities such as hospitals, schools, and transit hubs. We used mixed-effects logistic regression and machine learning (random forests) to investigate their association with enterovirus isolation (poliovirus and nonpolio enteroviruses) as an indicator of surveillance sensitivity. Four quarterly visits were made to 78 ES sites in 21 states of Nigeria, and ES site characteristic data were matched to 1345 samples with an average enterovirus prevalence among sites of 68% (range, 9%-100%). A larger estimated catchment population, high total dissolved solids, and higher pH were associated with enterovirus detection. A random forests model predicted "good" sites (enterovirus prevalence >70%) from measured site characteristics with out-of-sample sensitivity and specificity of 75%. Simple measurement of sewage properties and catchment population estimation could improve ES site selection and increase surveillance sensitivity.
Related Publications
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
December 2018,
Food and environmental virology,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
May 2019,
Viruses,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
October 2015,
Journal of infection in developing countries,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
January 1976,
Bulletin of the Pan American Health Organization,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
January 1963,
Archiv fur die gesamte Virusforschung,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
December 2019,
The American journal of tropical medicine and hygiene,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
May 2016,
The Journal of infectious diseases,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
March 2017,
Applied and environmental microbiology,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
January 2014,
Journal of virological methods,
Abdullahi Walla Hamisu, and
Isobel M Blake, and
Gerald Sume, and
Fiona Braka, and
Abdullateef Jimoh, and
Habu Dahiru, and
Mohammed Bonos, and
Raymond Dankoli, and
Ahmed Mamuda Bello, and
Kabir M Yusuf, and
Namadi M Lawal, and
Fatimah Ahmed, and
Zainab Aliyu, and
Doris John, and
Theresa E Nwachukwu, and
Michael F Ayeni, and
Nicksy Gumede-Moeletsi, and
Philippe Veltsos, and
Sidhartha Giri, and
Ira Praharaj, and
Angeline Metilda, and
Ananda Bandyopadhyay, and
Ousmane M Diop, and
Nicholas C Grassly
April 2024,
Food and environmental virology,
