Ion mobility spectrometry and ion mobility spectrometry/mass spectrometric characterization of dimenhydrinate. 1988

A H Lawrence, and A A Nanji
Unsteady Aerodynamics Laboratory, National Aeronautical Establishment, Ottawa, Ontario, Canada.

Positive and negative ion mobility spectra of dimenhydrinate are presented, and the calculated reduced mobility (K0) values for the most significant peaks are reported. Mass identification of the ionic species associated with the peaks in the ion mobility spectra was achieved by interfacing the ion mobility spectrometer to a mass spectrometer. The application of ion mobility spectrometry to the detection of dimenhydrinate and other drug residues on the hands of patients admitted to hospital with drug overdose is also discussed.

UI MeSH Term Description Entries
D004111 Dimenhydrinate A drug combination that contains diphenhydramine and theophylline. It is used for treating VERTIGO, MOTION SICKNESS, and NAUSEA associated with PREGNANCY. Diphenhydramine Theoclate,Apo-Dimenhydrinate,Aviomarin,Biodramina,Calm-X,Cinfamar,Contramareo,DMH,Dimen Heumann,Dimen Lichtenstein,Dimetabs,Dinate,Dramamine,Dramanate,Gravol,Marmine,Motion-Aid,Nausicalm,Reisegold,Reisetabletten Lünopharm,Reisetabletten Stada,Reisetabletten-ratiopharm,Rodovan,RubieMen,Superpep,Travel Well,TripTone,Vertigo-Vomex,Vomacur,Vomex A,Vomisin,Wehamine,Apo Dimenhydrinate,Calm X,Heumann, Dimen,Lichtenstein, Dimen,Lünopharm, Reisetabletten,Motion Aid,Reisetabletten ratiopharm,Stada, Reisetabletten,Theoclate, Diphenhydramine,Vertigo Vomex
D012996 Solutions The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed) Solution
D013053 Spectrophotometry The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.
D013058 Mass Spectrometry An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers. Mass Spectroscopy,Spectrometry, Mass,Spectroscopy, Mass,Spectrum Analysis, Mass,Analysis, Mass Spectrum,Mass Spectrum Analysis,Analyses, Mass Spectrum,Mass Spectrum Analyses,Spectrum Analyses, Mass

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