Biomaterial Database

Which Ultrasound Parameter Is More Accurate in the Diagnosis of Carpal Tunnel Syndrome: Cross-Sectional Area, Resistive Index, or Strain Ratio? 2020

Osman Ciloglu, and Feride Fatma Görgülü

From the Departments of Orthopaedic and Traumatology (OC) and Radiology (FFG), University of Health Sciences Adana Health Practice and Research Center, Adana, Turkey.

The aim of this study was to compare the accuracy of cross-sectional area (CSA), resistive index (RI), and strain ratio (SR) in carpal tunnel syndrome (CTS). This prospective and case-control study included patients with a diagnosis of CTS and a healthy control group. The participants were examined with an ultrasound Doppler system equipped with a high-resolution (5-18 MHz) linear probe (Philips L18-5). CSA, RI, and SR values were compared. CSA, RI, and SR were found to be effective tools to detect the presence of CTS (regardless of severity). The cut-off value of 11.25 mm for CSA had a sensitivity and specificity of 97.2% and 88.0%, respectively. The cut-off value of 0.740 for RI had a sensitivity and specificity of 94.4% and 94.0%, respectively. The cut-off value of 1.95 for SR had a sensitivity and specificity of 97.2% and 84.0%, respectively. In respect of the severity of CTS, ultrasound was found to be an effective method to classify severe CTS cases only. The CSA, SR, and RI seem to have excellent accuracy in the diagnosis of CTS. When the grading of severity is considered, ultrasound seems to be sensitive and specific in differentiating severe CTS cases from mild or moderate CTS cases.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002349	Carpal Tunnel Syndrome	Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)	Compression Neuropathy, Carpal Tunnel,Entrapment Neuropathy, Carpal Tunnel,Amyotrophy, Thenar, Of Carpal Origin,Median Neuropathy, Carpal Tunnel,Carpal Tunnel Syndromes,Syndrome, Carpal Tunnel,Syndromes, Carpal Tunnel
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000068598	Data Accuracy	A measure of scientific precision, exactness, or correctness of quantitative or qualitative values, relative to the actual or true measurements.	Data Quality,Accuracies, Data,Accuracy, Data,Data Accuracies,Data Qualities,Qualities, Data,Quality, Data
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D012680	Sensitivity and Specificity	Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	Specificity,Sensitivity,Specificity and Sensitivity