Biomaterial Database

Effects of the neuropeptide PLG (L-prolyl-leucyl-glycinamide) on writing pressure and speed in healthy subjects. 1988

K C Steinwachs, and H L Fehm

Department of Internal Medicine, University of Ulm, FRG.

There has been accumulating evidence that PLG influence behavior in humans after peripheral administration. In a randomized double blind study with 10 healthy male subjects in each group, the effect of 25 mg PLG i.v. on writing regulation was investigated and computer evaluated. The writing pressure test was selected as a sensitive parameter to ascertain an effect of PLG on motor behavior. As compared to the placebo group, PLG effects an increase of writing time and a reduction of writing pressure. The results suggested an peptide effect on writing performance in healthy subjects.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009842	Oligopeptides	Peptides composed of between two and twelve amino acids.	Oligopeptide
D004311	Double-Blind Method	A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.	Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014956	Writing	The act or practice of literary composition, the occupation of writer, or producing or engaging in literary work as a profession.