-transparent.png){kind=logo}
This study has shown that ileal and colonic mucosa contained roughly 1.2 microg/g of irPSTI. irPSTI from gastrointestinal mucosa eluted in a similar way to that of native PSTI after chromatographic separation and inhibited trypsin in a 1-1 molar way. The PSTI immunoreactive material was localized in the Paneth cells and the goblet cells in the small and large intestine. In normal gastric mucosa it was found in the foveolar cells while the acid and pepsinogen producing cells lacked PSTI immunoreactive material. In gastric mucosa with intestinal metaplasia a marked deficiency of PSTI was found. These findings indicate that gastrointestinal mucosa could be an additional source of irPSTI. Further studies are needed to elucidate if PSTI is involved in the defence of the gastrointestinal mucosa.
M Bohe, and
C Lindström, and
K Ohlsson
November 1990,
Gut,
M Bohe, and
C Lindström, and
K Ohlsson
September 1983,
Research communications in chemical pathology and pharmacology,
M Bohe, and
C Lindström, and
K Ohlsson
July 1988,
International journal of pancreatology : official journal of the International Association of Pancreatology,
M Bohe, and
C Lindström, and
K Ohlsson
November 2007,
The American journal of pathology,
M Bohe, and
C Lindström, and
K Ohlsson
January 1987,
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
M Bohe, and
C Lindström, and
K Ohlsson
May 1983,
Research communications in chemical pathology and pharmacology,
M Bohe, and
C Lindström, and
K Ohlsson
February 1995,
Nihon rinsho. Japanese journal of clinical medicine,
M Bohe, and
C Lindström, and
K Ohlsson
January 1976,
Methods in enzymology,
M Bohe, and
C Lindström, and
K Ohlsson
November 2004,
Nihon rinsho. Japanese journal of clinical medicine,
M Bohe, and
C Lindström, and
K Ohlsson
August 1999,
Nihon rinsho. Japanese journal of clinical medicine,
