Nasal Chondromesenchymal Hamartoma. 2020

Balamurugan Thirunavukkarasu, and Debajyoti Chatterjee, and Satyawati Mohindra, and Bishan Dass Radotra, and Shiv Jee Prashant
Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Nasal chondromesenchymal hamartoma (NCMH) is a rare, benign lesion of the sinonasal tract. It usually presents as a polypoid mass in infants and older children. Imaging studies and endoscopy are required to delineate the extent of the lesion and aid in its excision. This unusual lesion is composed of proliferating mesenchymal and cartilaginous elements. Recently, a genetic association between NCMH and DICER1 mutation has been established. It is important for pathologists to be familiar with this entity to avoid misdiagnosis since the lesion is benign and surgical excision is curative.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D009668 Nose Diseases Disorders of the nose, general or unspecified. Nasal Diseases,Nasal Disorders,Disease, Nasal,Disease, Nose,Diseases, Nasal,Diseases, Nose,Disorder, Nasal,Disorders, Nasal,Nasal Disease,Nasal Disorder,Nose Disease
D006222 Hamartoma A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area. Hamartomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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