The changes of intracranial hemodynamics were studied at the early stage of vasorenal arterial hypertension in 7 rabbits. During first 4-5 weeks of the hypertension development, the AP increased to 170 mm Hg which was followed by a drop in the blood flow by 15% in the cortex and by 19% in white matter. The blood flow increment in response to inhalation of CO2 lowered from initial 120% to 106% in the cortex and from 126% to 109% in white matter. The data on the brain tissue impedance suggested an absence of the hyperhydration of extracellular space. A mathematical model of the development of cerebral hemodynamic shift was suggested for this form of arterial hypertension, and the hypothesis was formed that vasoconstrictor response of the brain resistive vessels decreased cerebral blood flow thus preventing th shift of the Starling equilibrium and the fluid outflow from the vascular bed.