Evaluation of Pancreatic Lesions With Endoscopic Ultrasound and Fine Needle Aspiration. 2020

Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
Department of Surgery, Queen Mary Hospital, 25809The University of Hong Kong, China.

Background. Endoscopic ultrasound (EUS) and fine-needle aspiration (FNA) are commonly used for assessing pancreatic lesions. This study aimed to evaluate the diagnostic yield and accuracy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in a single tertiary institution. Methods. Consecutive patients who underwent EUS-FNA of the pancreas at Queen Mary Hospital, Hong Kong, from January 2015 to March 2016 were retrospectively reviewed. Endoscopic findings and FNA results were analysed. For patients who subsequently underwent surgical resection of pancreatic lesion, EUS-FNA diagnoses were compared to histopathological findings of surgical specimens to determine its diagnostic accuracy. Results. One hundred twelve EUS-FNA were performed in 99 patients within the study time period and were included for analysis. Sixty-six (66.7%) pancreatic lesions were solid in nature and 33 (33.3%) were cystic. The overall diagnostic yield of EUS-FNA was 70.5% (n = 79). On multivariate analysis, more passes of needle were associated with a higher diagnostic yield (odds ratio = 2.000, P = .049). 57.1% (n = 64) of EUS-FNA results had an impact on management. Sixteen patients with diagnostic EUS-FNA subsequently underwent surgery for resection of the pancreatic lesion. Upon correlation to the histopathological findings of surgical specimens, there were 12 true-positive, 2 true-negative, 0 false-positive, and 2 false-negative cases. Sensitivity was 85.7%, specificity was 100%, positive predictive value was 100%, and negative predictive value was 50%. The diagnostic accuracy of EUS-FNA was 87.5%. Conclusion. EUS-FNA is accurate and reliable for diagnosing pancreatic lesions.

UI MeSH Term Description Entries
D010179 Pancreas A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
D010190 Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). Cancer of Pancreas,Pancreatic Cancer,Cancer of the Pancreas,Neoplasms, Pancreatic,Pancreas Cancer,Pancreas Neoplasms,Pancreatic Acinar Carcinoma,Pancreatic Carcinoma,Acinar Carcinoma, Pancreatic,Acinar Carcinomas, Pancreatic,Cancer, Pancreas,Cancer, Pancreatic,Cancers, Pancreas,Cancers, Pancreatic,Carcinoma, Pancreatic,Carcinoma, Pancreatic Acinar,Carcinomas, Pancreatic,Carcinomas, Pancreatic Acinar,Neoplasm, Pancreas,Neoplasm, Pancreatic,Neoplasms, Pancreas,Pancreas Cancers,Pancreas Neoplasm,Pancreatic Acinar Carcinomas,Pancreatic Cancers,Pancreatic Carcinomas,Pancreatic Neoplasm
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D061765 Endoscopic Ultrasound-Guided Fine Needle Aspiration Conducting a fine needle biopsy with the aid of ENDOSCOPIC ULTRASONOGRAPHY. EUS-FNA,Endoscopic Ultrasound Guided Fine Needle Aspiration
D019160 Endosonography Ultrasonography of internal organs using an ultrasound transducer sometimes mounted on a fiberoptic endoscope. In endosonography the transducer converts electronic signals into acoustic pulses or continuous waves and acts also as a receiver to detect reflected pulses from within the organ. An audiovisual-electronic interface converts the detected or processed echo signals, which pass through the electronics of the instrument, into a form that the technologist can evaluate. The procedure should not be confused with ENDOSCOPY which employs a special instrument called an endoscope. The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously. Echo-Endoscopy,Endoscopic Ultrasonography,Endoscopy, Echo,Endoscopy, Ultrasonic,Ultrasonic Endoscopy,Ultrasonography, Endoscopic,Echo Endoscopies,Echo Endoscopy,Echo-Endoscopies,Endoscopic Ultrasonographies,Endoscopies, Echo,Endoscopies, Ultrasonic,Endosonographies,Ultrasonic Endoscopies,Ultrasonographies, Endoscopic

Related Publications

Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
November 1997, Endoscopy,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
June 2012, Clinical endoscopy,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
January 2022, International journal of environmental research and public health,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
January 2015, Endoscopic ultrasound,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
January 2020, Gastroenterologia y hepatologia,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
January 2016, North American journal of medical sciences,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
June 2019, Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
May 2014, Journal of hepato-biliary-pancreatic sciences,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
March 2018, European review for medical and pharmacological sciences,
Yan Luk, and Wong Hoi She, and Felix Che Lok Chow, and Ka Wing Ma, and Simon Hing Yin Tsang, and Wing Chiu Dai, and Tan To Cheung, and Chung Mau Lo
November 2023, Cardiovascular and interventional radiology,
Copied contents to your clipboard!