The aim of the study was to determine the correlation between implanted IOL material type and posterior capsule opacification. At 12 month, there was no statistically and visually significant changes in all controlled groups. At 18 month, 3 eyes (5.2%) from Group 2 and 1 eye (5.8%) from hydrophobic arm of Group 3 had visually significant PCO and underwent Nd:YAG laser posterior capsulotomy. 8 eyes (10.8%) in group 1 and 3 eyes (17.6%) in hydrophilic arm of Group 3 required Nd:YAG laser posterior capsulotomy. At 3, 6, and 12 month compared to baseline (1 month postoperatively), there was no statistically and clinically significant difference in visual acuity and subjective refraction between the groups. At 12 month, 3 patients (4%) from group 1 and 1 patient (6%) from hydrophilic arm of group 3 complained of glare sensitivity, especially in mesopic conditions. At that point, interestingly, no patient from Group 2 and hydrophobic arm of Group 3 complained about glare sensitivity. In terms of UCDVA, 68 eyes of group 1 (91%) achieved 20/20 or better distance vision, 71 eyes (96%) achieved 20/25 distance vision. In Group 2, 50 eyes (87%) achieved 20/20 or better distance vision, 52 eyes (92%) achieved 20/25 distance vision. In Group 3, 14 eyes (82%) of hydrophilic arm achieved 20/20 or better distance vision and 15 eyes (88%) achieved 20/25 distance vision. In hydrophobic arm of group 3, 16 eyes (94%) achieved 20/20 or better distance vision. UCDVA was examined with ClearChart 2 Digital Acuity System (Reichert Technologies), using Landolt C optotypes. Biometry data was acquired by IOLMaster-500 (Carl Zeiss, Meditec). Contrast sensitivity was evaluated with ClearChart 2 Digital Acuity System (Reichert Technologies), using Pelli-Robson Contrast Sensitivity Chart. At 1, 3, 6, month there was no statistically significant difference between controlled groups in terms of contrast sensitivity. At 12 month, 5 patients (6%) from Group 1 and 3 patients (17%) from Group 3 hydrophilic arm had slightly decreased contrast sensitivity. There was no changes in contrast sensitivity in eyes of Group 2 at 12 month period. The study is still ongoing. The patients will be evaluated at 24 month and 36 month postoperatively.