Outcomes of Glaucoma Drainage Devices in Childhood Glaucoma. 2020

Abdelrahman M Elhusseiny, and Deborah K VanderVeen
Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School , Boston, MA, USA.

OBJECTIVE Angle surgery is the gold standard for the management of many types of childhood glaucoma, yet glaucoma drainage devices (GDD) are effective tools for refractory advanced cases or secondary childhood glaucomas. The purpose of this article is to review recently published literature focused on the use of GDDs for pediatric glaucoma, including GDD general principles and surgical outcomes. METHODS Literature review of various electronic databases was performed. RESULTS 71 papers were reviewed for outcomes of GDD in childhood glaucomas. Success rates were usually defined by intraocular pressure (IOP) of 5-22 mmHg, with or without medications. Success rates were typically higher for non-valved GDDs but varied by length of follow-up. Non-valved GDDs afford lower and longer-lasting IOP control in pediatric eyes than valved GDD, however, no randomized controlled trials exist in childhood glaucoma. CONCLUSIONS Various designs of GDDs are available for management of childhood glaucoma with good short-term success rates; individual patient factors should be taken into consideration when selecting a specific device.

UI MeSH Term Description Entries
D007429 Intraocular Pressure The pressure of the fluids in the eye. Ocular Tension,Intraocular Pressures,Ocular Tensions,Pressure, Intraocular,Pressures, Intraocular,Tension, Ocular,Tensions, Ocular
D011474 Prosthesis Design The plan and delineation of prostheses in general or a specific prosthesis. Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005901 Glaucoma An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) Glaucomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D019919 Prosthesis Implantation Surgical insertion of a prosthesis. Implantation, Prosthesis,Implantations, Prosthesis,Prosthesis Implantations
D020327 Glaucoma Drainage Implants Devices, usually incorporating unidirectional valves, which are surgically inserted in the sclera to maintain normal intraocular pressure. Aqueous Humor Shunt,Aqueous Shunt,Aqueous Shunts,Baerveldt Implant,Baerveldt Implants,Glaucoma Drainage Implant,Glaucoma Filtration Implant,Glaucoma Filtration Implants,Krupin Valve,Krupin Valves,Aqueous Humor Shunts,Drainage Implant, Glaucoma,Drainage Implants, Glaucoma,Filtration Implant, Glaucoma,Filtration Implants, Glaucoma,Implant, Baerveldt,Implant, Glaucoma Drainage,Implant, Glaucoma Filtration,Implants, Baerveldt,Implants, Glaucoma Drainage,Implants, Glaucoma Filtration,Shunt, Aqueous,Shunt, Aqueous Humor,Shunts, Aqueous,Shunts, Aqueous Humor,Valve, Krupin,Valves, Krupin

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